Vinorelbine
Suppliers
Names
[ CAS No. ]:
71486-22-1
[ Name ]:
Vinorelbine
[Synonym ]:
Methyl (2β,3β,4β,5α,12β,19α)-4-acetoxy-15-[(12S)-16-ethyl-12-(methoxycarbonyl)-1,10-diazatetracyclo[12.3.1.0.0]octadeca-3(11),4,6,8,15-pentaen-12-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate
8-methylsulfanyl-5-nonylsulfanyl-quinoline
aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12β,19α)-
vinorebline
3',4'-didehydro-4'-desoxy-8'-norvincaleucoblastine
5-Nonylthio-8-methylthio-chinolin
5'-noranhydrovinblastine
vinorelbene
Methyl (2β,3β,4β,5α,12β,19α)-4-acetoxy-15-[(12S)-16-ethyl-12-(methoxycarbonyl)-1,10-diazatetracyclo[12.3.1.0.0]octadeca-3(11),4,6,8,15-pentaen-12-yl]-3-hydroxy-16-methox y-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate
Quinoline,8-(methylthio)-5-(nonylthio)
Vinorelbine
Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, meth ;yl ester, (2β,3β,4β,5α,12β,19α)-
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Molecular Formula ]:
C45H54N4O8
[ Molecular Weight ]:
778.932
[ Exact Mass ]:
778.394165
[ PSA ]:
133.87000
[ LogP ]:
4.69
[ Index of Refraction ]:
1.676
[ Storage condition ]:
2-8C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RD2530000
- CHEMICAL NAME :
- C'-Norvincaleukoblastine, 3',4'-didehydro-4'-deoxy-
- CAS REGISTRY NUMBER :
- 71486-22-1
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C45-H54-N4-O8
- MOLECULAR WEIGHT :
- 779.03
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 26 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTKRDX Gan to Kagaku Ryoho. Cancer and Chemotherapy. (1-8-9 Yaesu, Chuo-ku, Tokyo 103, Japan) V.1- 1974- Volume(issue)/page/year: 10,1050,1983