3-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]carbamoyl]propanoic acid

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Names

[ CAS No. ]:
71576-05-1

[ Name ]:
3-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]carbamoyl]propanoic acid

[Synonym ]:
3-[[4-(4-CHLOROPHENYL)-1,3-THIAZOL-2-YL]CARBAMOYL]PROPANOIC ACID
4-((4-(4-Chlorophenyl)-2-thiazolyl)amino)-4-oxobutanoic acid
4-{[4-(4-chlorophenyl)-1,3-thiazol-2-yl]amino}-4-oxobutanoic acid
Butanoic acid,4-((4-(4-chlorophenyl)-2-thiazolyl)amino)-4-oxo
Acide N(p-chlorophenyl-4 thiazolyl-2) succinamique [French]
F 1683
4-(4-(4-chlorophenyl)thiazol-2-ylamino)-4-oxobutanoic acid

Chemical & Physical Properties

[ Density]:
1.479g/cm3

[ Molecular Formula ]:
C13H11ClN2O3S

[ Molecular Weight ]:
310.75600

[ Exact Mass ]:
310.01800

[ PSA ]:
111.02000

[ LogP ]:
3.91630

[ Index of Refraction ]:
1.657

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EK7761172
CHEMICAL NAME :
Butanoic acid, 4-((4-(4-chlorophenyl)-2-thiazolyl)amino)-4-oxo-
CAS REGISTRY NUMBER :
71576-05-1
LAST UPDATED :
199609
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C13-H11-Cl-N2-O3-S
MOLECULAR WEIGHT :
310.77

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0001727

Synthetic Route

Precursor & DownStream

Precursor

  • Succinic anhydride
  • 2-amino-4-(4-chlorophenyl)thiazole
  • 1-(4-Chlorophenyl)ethanone
  • 2-Bromo-4'-chloroacetophenone

DownStream


Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • Propan-2-yl 2-[(cyclopropylamino)methyl]-1,3-oxazole-4-carboxylate
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • N-(3-acetylphenyl)-2'-(butan-2-yl)-1'-oxo-1',4'-dihydro-2'H-spiro[cyclopentane-1,3'-isoquinoline]-4'-carboxamide
  • tert-Butyl-DL-alanine