(1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol
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Names
[ CAS No. ]:
716-61-0
[ Name ]:
(1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol
[Synonym ]:
2-Amino-1-(4-nitrophenyl)-1,3-propanediol
2-amino-1-(4-nitrophenyl)propane-1,3-diol
D-(-)-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol
(1R,2R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol
D-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
1,3-Propanediol, 2-amino-1-(4-nitrophenyl)-
D-threo-(-)-2-Amino-1-(p-nitrophenyl)-1,3-propanediol
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
1-(p-nitrophenyl)-2-amino-1,3-propanediol
MFCD00078126
1,3-Propanediol, 2-amino-1- (p-nitrophenyl)-
1,3-Propanediol, 2-amino-1- (4-nitrophenyl)-
1,3-Propanediol, 2-amino-1-(p-nitrophenyl)-, D-threo-(-)-
EINECS 211-938-7
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
451.9±45.0 °C at 760 mmHg
[ Melting Point ]:
163-165ºC
[ Molecular Formula ]:
C9H12N2O4
[ Molecular Weight ]:
212.203
[ Flash Point ]:
227.1±28.7 °C
[ Exact Mass ]:
212.079712
[ PSA ]:
112.30000
[ LogP ]:
0.13
[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C
[ Index of Refraction ]:
1.630
[ Storage condition ]:
−20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TY3100000
- CHEMICAL NAME :
- 1,3-Propanediol, 2-amino-1-(p-nitrophenyl)-, D-threo-(-)-
- CAS REGISTRY NUMBER :
- 716-61-0
- LAST UPDATED :
- 199406
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C9-H12-N2-O4
- MOLECULAR WEIGHT :
- 212.23
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 2 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 320,207,1994
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26
[ RIDADR ]:
UN 3259
[ WGK Germany ]:
3
[ RTECS ]:
TY3100000
Articles
Yao Xue Xue Bao 25(6) , 430-4, (1990)
Threo (-) or (+)-1-(p-nitrophenyl)-1,3-dihydroxypropylamine-2 was found to be a useful resolving agent for racemic gossypol. The optical and chemical stability of the condensate of enantiomeric gossyp...
Mol. Genet. Metab. 66(4) , 314-9, (1999)
The CLN3 gene, which encodes the protein whose absence is responsible for Batten disease, the most common inherited neurovisceral storage disease of childhood, was identified in 1995. The function of ...
J. Chromatogr. A. 170(1) , 282-7, (1979)