(+/-)-4-HYDROXYDEBRISOQUIN

Suppliers

Names

[ Name ]:
(+/-)-4-HYDROXYDEBRISOQUIN

[Synonym ]:
6-Chlor-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin
8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
C16H16ClNO2
1H-3-Benzazepine-7,8-diol,6-chloro-2,3,4,5-tetrahydro-1-phenyl
6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
6-chloro-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol
6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol
MFCD00153782

Chemical & Physical Properties

[ Density]:
1.299 g/cm3

[ Boiling Point ]:
467.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₆H₁₇BrClNO₂

[ Molecular Weight ]:
370.66900

[ Flash Point ]:
236.4ºC

[ Exact Mass ]:
369.01300

[ PSA ]:
52.49000

[ LogP ]:
4.31570

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
22-26-36

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

6-chloro-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Styrene oxide
N-(2-Hydroxy-2-phenethyl)-N-[2-(2'-chlor-3',4'-dimethoxyphenyl)-ethyl]-amin
2-(2-Chloro-3,4-dimethoxyphenyl) ethylamine
(2-chloro-3,4-dimethoxyphenyl)acetonitrile

DownStream

Articles

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nat. Chem. Biol. 5 , 765-71, (2009)

Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened...

Membrane properties of striatal direct and indirect pathway neurons in mouse and rat slices and their modulation by dopamine.

PLoS ONE 8(3) , e57054, (2013)

D1 and D2 receptor expressing striatal medium spiny neurons (MSNs) are ascribed to striatonigral ("direct") and striatopallidal ("indirect") pathways, respectively, that are believed to function antag...

Developmental increase in D1-like dopamine receptor-mediated inhibition of glutamatergic transmission through P/Q-type channel regulation in the basal forebrain of rats.

Eur. J. Neurosci. 32(4) , 579-90, (2010)

Whole-cell patch-clamp recordings of non-N-methyl-d-aspartate glutamatergic excitatory postsynaptic currents (EPSCs) were carried out from cholinergic neurons in slices of basal forebrain (BF) of deve...

(+/-)-4-HYDROXYDEBRISOQUIN
(+)-4(S)-hydroxy-2-cyclopenten-1(R)-yl N-mesyl-(S)-phenylalaninate
(+/-)-4-benzyl-2-(2-ethoxyphenoxymethyl)morpholine
(+)-4-methylsulfanyl-1.2-diphenyl-butanone-(1)
(+/-)-4-(2'-Methylbutyl)phenyl-4'-octylbiphenyl-4-carboxylate
(+-)-4-hydroxy-4,8-dimethyl-6-oxo-nonanoic acid-lactone