Benzenemethanol, alpha,alpha-bis(trifluoromethyl)-

Names

[ CAS No. ]:
718-64-9

[ Name ]:
Benzenemethanol, alpha,alpha-bis(trifluoromethyl)-

[Synonym ]:
1,1,1,3,3,3-hexafluoro-2-phenylpropan-2-ol
EINECS 211-943-4
MFCD00040983

Chemical & Physical Properties

[ Density]:
1.45 g/mL at 25 °C(lit.)

[ Boiling Point ]:
160 °C(lit.)

[ Molecular Formula ]:
C₉H₆F₆O

[ Molecular Weight ]:
244.13400

[ Flash Point ]:
140 °F

[ Exact Mass ]:
244.03200

[ PSA ]:
20.23000

[ LogP ]:
2.99880

[ Index of Refraction ]:
n20/D 1.415(lit.)

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
UN 1987 3/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2906299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Trifluoromethane
Benzoyl chloride
n-benzoylimidazole
(Trifluoromethyl)trimethylsilane
(1,1,1,3,3,3-hexafluoro-2-phenylpropan-2-yl)oxy-trimethylsilane
Pentafluorophenyl Benzoate
Benzoic anhydride
2,2,2-Trifluoroacetophenone
Sodium perfluoroacetate
Hexafluoroacetone

DownStream

heptafluoroisopropylbenzene 98
2-(3-aminophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol
Benzenemethanol,3-nitro-a,a-bis(trifluoromethyl)-
9-chloro-7,7-bis(trifluoromethyl)-9$l^{3}-ioda-8-oxabicyclo[4.3.0]nona-1,3,5-triene
1,1,1,3,3,3-hexafluoro-2-phenyl-propan-2-ol

Customs

[ HS Code ]: 2906299090

[ Summary ]:
2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Structure-activity relationship of trifluoromethyl-containing metallocenes: electrochemistry, lipophilicity, cytotoxicity, and ROS production.

ChemMedChem 9(6) , 1188-94, (2014)

We report the synthesis of trifluoromethylated metallocenes (M=Fe, Ru) and related metal-free compounds for comparison of their biological properties with the aim to establish structure-activity relat...

Single electron transfer-living radical polymerization of methyl methacrylate in fluoroalcohol: Dual control over molecular weight and tacticity. Wang W, et al.

J. Polym. Sci. A Polym. Chem. 47(22) , 6316-6327, (2009)

Cyclic alkoxyamine-initiator tethered by azide/alkyne-“click”-chemistry enabling ring-expansion vinyl polymerization providing macrocyclic polymers. Narumi A, et al.

J. Polym. Sci. A Polym. Chem. 48(15) , 3402-3416, (2010)

BIS[ALPHA,ALPHA-BIS(TRIFLUOROMETHYL)BENZENEMETHANOLATO]DIPHENYLSULFUR
Benzenemethanol, alpha,alpha-dimethyl-, phenylcarbamate (9CI)
Benzenemethanol, alpha,alpha,3-triethyl-4-hydroxy- (9CI)
(S)-ALPHA,ALPHA-BIS(4-FLUOROPHENYL)-2-PYRROLIDINEMETHANOL
1-[2-[(2R)-4-[2-[3,5-Bis(trifluoromethyl)phenyl]acetyl]-2-(3,4-dichlorophenyl)-2-morpholinyl]ethyl]-alpha,alpha-dimethyl-4-piperidineacetamide
2-Pyrrolidinemethanol, alpha,alpha-bis(phenylmethyl)-1-((bromophenyl)m ethyl)-, hydrochloride
2-{2-Azabicyclo[3.1.0]hexan-2-yl}ethan-1-amine
2-(Bromomethyl)-1-ethyl-4-fluorobenzene
(2S,3aS,6aS)-2-(azidomethyl)-octahydrocyclopenta[b]pyrrole
2-Isocyano-3'-methoxy-1,1'-biphenyl
tert-butyl N-(6-bromo-2-fluoro-3-methylphenyl)carbamate
(5-Methyl-1,2-oxazol-3-yl)methyl chloroformate
(2-Methyl-5-nitrophenyl)methanesulfonamide
Methyl 5-chloro-4-(cyclopropylmethoxy)-2-fluorobenzoate
6-Ethynylnaphthalene-2-carbaldehyde
6-chloro-3-(2-nitroethyl)-1H-indole

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