Dihydroartemisinin

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Names

[ CAS No. ]:
71939-50-9

[ Name ]:
Dihydroartemisinin

[Synonym ]:
Dihydroartemisinin
Dihydroartemisin
3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol, decahydro-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-
Cotecxin
Dihydroginghaosu
(1S,4S,7R,8S,11R,12S,13R)-1,7,11-Trimethyl-3,5,14,15-tetraoxatetracyclo[10.3.1.0.0]hexadecan-6-ol
MFCD00274495
(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-Trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0.0]hexadecan-10-ol
Alaxin
[3H]-(10R/S)-Artenimol
Salaxin
artenimol
3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10-ol, decahydro-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-
(3R,5aS,6R,8aS,9R,12S,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol
(3R,5aS,6R,8aS,9R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol
dihyhydroartemisinin
DHQHS 2
(5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol
3,12-Methano-5aH,7H-1,2,5-trioxepino[3,4-j][2]benzopyran-7-ol, octahydro-3,8,11-trimethyl-, (3S,5aS,8R,8aS,11R,12S,12aR)-
Dihydroarteminisin
dihydroquinghaosu
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol
Cotexin
Dihydroqinghaosu

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
375.6±42.0 °C at 760 mmHg

[ Melting Point ]:
144-149ºC

[ Molecular Formula ]:
C15H24O5

[ Molecular Weight ]:
284.348

[ Flash Point ]:
181.0±27.9 °C

[ Exact Mass ]:
284.162384

[ PSA ]:
57.15000

[ LogP ]:
2.27

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.543

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Hazard Codes ]:
T+

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

Synthetic Route

Precursor & DownStream

Precursor

  • Artemisinin
  • alpha-Dihydroartemisinin

DownStream

  • Artesunate
  • alpha-Dihydroartemisinin
  • (3R,12aR)-3,6α,9β-Trimethyl-3β,12α-epoxy-3,4,5,5aα,6,7,8,8aα,9,10-decahydro-10α-ethoxypyrano[4,3-j]-1,2-benzodioxepin
  • Artemotil
  • anhydrodihydroartemisinin
  • deoxyartemisinin
  • (2S,3R,6R)-2-(3-oxobutyl)-3-methyl-6-[(R)2-propanal]-cyclohexanone
  • (2S,3R,6S)-2-(3-oxobutyl)-3-methyl-6-[(R)2-propanal]-cyclohexanone
  • (2S,3R,6RS)-2-(3-Oxobutyl)-3-Methyl-6-[(R)-2-propanal]cyclohexanone
  • Artemether

Related Compounds

  • Dihydroartemisinin
  • dihydroartemisinin
  • dihydroartemisinin
  • Dihydroartemisinin
  • Dihydroartemisinin-d3
  • dihydroartemisinin acetate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 1-(3,4-difluorobenzoyl)-N-(thiophen-2-ylmethyl)azetidine-3-carboxamide
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide