Fmoc-Glu(OtBu)-OH

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Names

[ CAS No. ]:
71989-18-9

[ Name ]:
Fmoc-Glu(OtBu)-OH

[Synonym ]:
(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoic acid
EINECS 276-253-8
(2S)-5-tert-Butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
MFCD00037135
L-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester
Fmoc-L-glutamic acid 5-tert-butyl ester
Fmoc-L-glutamicacid5-tert-butylester

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
633.5±55.0 °C at 760 mmHg

[ Melting Point ]:
83-90 °C

[ Molecular Formula ]:
C₂₄H₂₇NO₆

[ Molecular Weight ]:
425.474

[ Flash Point ]:
337.0±31.5 °C

[ Exact Mass ]:
425.183838

[ PSA ]:
101.93000

[ LogP ]:
5.26

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.571

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-27-36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Fmoc-Glu(t-Bu)-1,1-dimethylallyl ester
H-Glu(OtBu)-OH
Fmoc-Osu
9H-Fluoren-9-ylmethyl pentafluorophenyl carbonate
9H-fluoren-9-ylmethyl 2,5-dioxopyrrolidine-1-carboxylate
L-glutamic acid
Isobutylene

DownStream

Fmoc-Glu-OMe
L-glutamic acid
H-Glu(OtBu)-OH
Fmoc-Glu(OtBu)-OPfp
Delta-Sleep Inducing Peptide trifluoroacetate salt
Fmoc-L-Glu(tBu)-OSu
Fmoc-L-Glutamol(tBu)
Fmoc-D-Glu-OH
H-Glu(Glu-OH)-OH
Fmoc-Glu-Obzl

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