Fmoc-Glu(OtBu)-OH

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Names

[ CAS No. ]:
71989-18-9

[ Name ]:
Fmoc-Glu(OtBu)-OH

[Synonym ]:
(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoic acid
EINECS 276-253-8
(2S)-5-tert-Butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
MFCD00037135
L-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester
Fmoc-L-glutamic acid 5-tert-butyl ester
Fmoc-L-glutamicacid5-tert-butylester

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
633.5±55.0 °C at 760 mmHg

[ Melting Point ]:
83-90 °C

[ Molecular Formula ]:
C24H27NO6

[ Molecular Weight ]:
425.474

[ Flash Point ]:
337.0±31.5 °C

[ Exact Mass ]:
425.183838

[ PSA ]:
101.93000

[ LogP ]:
5.26

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.571

[ Storage condition ]:
2~8°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-27-36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Precursor & DownStream

Precursor

  • Fmoc-Glu(t-Bu)-1,1-dimethylallyl ester
  • H-Glu(OtBu)-OH
  • Fmoc-Osu
  • 9H-Fluoren-9-ylmethyl pentafluorophenyl carbonate
  • 9H-fluoren-9-ylmethyl 2,5-dioxopyrrolidine-1-carboxylate
  • L-glutamic acid
  • Isobutylene

DownStream

  • Fmoc-Glu-OMe
  • L-glutamic acid
  • H-Glu(OtBu)-OH
  • Fmoc-Glu(OtBu)-OPfp
  • Delta-Sleep Inducing Peptide trifluoroacetate salt
  • Fmoc-L-Glu(tBu)-OSu
  • Fmoc-L-Glutamol(tBu)
  • Fmoc-D-Glu-OH
  • H-Glu(Glu-OH)-OH
  • Fmoc-Glu-Obzl

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Related Compounds

  • Fmoc-Glu(OtBu)-OH
  • Fmoc-Glu(OtBu)-OH
  • Fmoc-Glu(OtBu)-OH
  • Fmoc-Glu(OtBu)-OH-15N
  • fmoc-glu(otbu)-oh h2o
  • Boc-Ser(Fmoc-Glu(OtBu))-OH
  • 2-{1-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]azetidin-3-yl}-2H-1,2,3-triazole
  • N-[(4-Thiomorpholin-4-yloxan-4-yl)methyl]cyclobutanecarboxamide
  • 2-{5-[(1,3,4-Oxadiazol-2-yl)methyl]-octahydropyrrolo[3,4-c]pyrrol-2-yl}-5-(trifluoromethyl)pyridine
  • 1-{4-[(5-Chloropyrimidin-2-yl)oxy]piperidin-1-yl}-3,3-dimethylbutan-1-one
  • 5-Ethyl-4-methyl-6-[4-(6-methylpyrimidin-4-yl)piperazin-1-yl]pyrimidine
  • N-{[4-(thiomorpholin-4-yl)oxan-4-yl]methyl}-6-(trifluoromethyl)pyridine-3-carboxamide
  • 3-methoxy-N-methyl-N-({1-[(oxolan-2-yl)methyl]piperidin-4-yl}methyl)pyrazin-2-amine
  • 3-[1-(9-methyl-9H-purin-6-yl)pyrrolidin-3-yl]-1,3-oxazolidin-2-one
  • 4-{[4-(6-Cyclopropylpyridazin-3-yl)piperazin-1-yl]methyl}-1-methyl-1,2-dihydropyridin-2-one
  • 4-{Octahydrocyclopenta[c]pyrrol-2-yl}-2-(trifluoromethyl)pyridine
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