GSK-189254

Suppliers

Names

[ CAS No. ]:
720690-73-3

[ Name ]:
GSK-189254

[Synonym ]:
6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methylnicotinamide
6-((3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy)-N-methyl-3-pyridinecarboxamide
GSK-189254
unii-5t4tx6co53
3-Pyridinecarboxamide, 6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-
GSK189254A
GSK-189254A
6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methylpyridine-3-carboxamide

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
545.0±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₁H₂₅N₃O₂

[ Molecular Weight ]:
351.442

[ Flash Point ]:
283.4±30.1 °C

[ Exact Mass ]:
351.194672

[ PSA ]:
57.95000

[ LogP ]:
3.29

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.605

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol
6-Chloro-N-methylnicotinamide
N-methyl-6-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yloxy)-3-pyridinecarboxamide
Cyclobutanone
6-Chloronicotinoyl chloride
6-Chloronicotinic acid
7-methoxy-3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
2,3,4,5-TETRAHYDRO-7-METHOXY-1H-BENZO[D]AZEPINE
8-Methoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one
3-Methoxyphenylacetic acid