Prilocaine

Suppliers

Names

[ CAS No. ]:
721-50-6

[ Name ]:
Prilocaine

[Synonym ]:
UNII:046O35D44R
Astra 1515
Propanamide, N-(2-methylphenyl)-2-(propylamino)-
Astra 1512
N-(2-méthylphényl)-2-(propylamino)propanamide
EINECS 211-957-0
prilocainum [INN_la]
N-(2-Methylphenyl)-N-propylalaninamide
Citanest
Pricocaine
N-(2-Methylphenyl)-2-(propylamino)propanamid
MFCD00048681
N-(2-methylphenyl)-N2-propylalaninamide
prilocaine
Propitocaine

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
361.6±25.0 °C at 760 mmHg

[ Melting Point ]:
37-38ºC

[ Molecular Formula ]:
C13H20N2O

[ Molecular Weight ]:
220.311

[ Flash Point ]:
134.3±23.3 °C

[ Exact Mass ]:
220.157562

[ PSA ]:
41.13000

[ LogP ]:
1.74

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.543

[ Storage condition ]:
-20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UG5760000
CHEMICAL NAME :
o-Propionotoluidide, 2-(propylamino)-
CAS REGISTRY NUMBER :
721-50-6
LAST UPDATED :
199706
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C13-H20-N2-O
MOLECULAR WEIGHT :
220.35

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
231 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 61,455,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
519 mg/kg
TOXIC EFFECTS :
Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea Skin and Appendages - hair
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 61,455,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
59900 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 61,455,1965

Safety Information

[ HS Code ]:
2924299090

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • prilocaine
  • Prilocaine HC
  • D-(-)-Prilocaine
  • Lidocaine/prilocaine
  • o-Desmethyl prilocaine
  • Prilocaine impurity A [EP]
  • 1,4-dimethyl-1H-pyrazol-3-amine hydrochloride
  • 3-(2-Fluoro-4-nitrophenoxy)azetidine
  • 3-(azetidin-3-yloxy)-N,N-dimethylaniline
  • 3-(Benzylsulfanyl)azetidine
  • Rel-benzyl ((3R,4R)-3-fluoropiperidin-4-yl)carbamate
  • Benzenemethanamine, 2,4-dibromo-N-(2-chloro-4-nitrophenyl)-I+/--methyl-
  • Benzonitrile, 2-chloro-5-[[1-(2,4-dibromophenyl)ethyl]amino]-
  • Ethyl 2-tert-butyl-4-(pyridin-3-yl)pyrimidine-5-carboxylate
  • 5-(chloromethyl)-1-cyclobutyl-1H-1,2,3,4-tetrazole
  • (2R,6S)-6-Phenyl-piperidine-2-carboxylic acid hydrochloride
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