Fomesafen

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Names

[ CAS No. ]:
72178-02-0

[ Name ]:
Fomesafen

[Synonym ]:
5-[2-chloro-4-(trifluoromethyl)phenoxy]-N-(methanesulfonyl)-2-nitrobenzamide
Benzamide, 5-[2-chloro-4-(trifluoromethyl)phenoxy]-N-(methylsulfonyl)-2-nitro-
5-[2-chloro-4-(trifluoromethyl)phenoxy]-N-methylsulfonyl-2-nitrobenzamide
Benzenecarboximidic acid, 5-[2-chloro-4-(trifluoromethyl)phenoxy]-N-(methylsulfonyl)-2-nitro-
MFCD01632756
EINECS 276-439-9
5-[2-Chloro-4-(trifluoromethyl)phenoxy]-N-(methylsulfonyl)-2-nitrobenzenecarboximidic acid
5-(2-chloro-α,α,α-trifluoro-p-tolyloxy)-N-mesyl-2-nitrobenzamide
fomesafen [ANSI]
Fomesafen
5-[2-Chloro-4-(trifluoromethyl)phenoxy]-N-(methylsulfonyl)-2-nitrobenzamide
WS1&MVR BNW EOR BG DXFFF
Fomesafene

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
531.4±60.0 °C at 760 mmHg

[ Melting Point ]:
220-221°C

[ Molecular Formula ]:
C15H10ClF3N2O6S

[ Molecular Weight ]:
438.763

[ Flash Point ]:
275.2±32.9 °C

[ Exact Mass ]:
437.990021

[ PSA ]:
126.67000

[ LogP ]:
3.58

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.586

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CV2475000
CHEMICAL NAME :
Benzamide, 5-(2-chloro-4-(trifluoromethyl)phenoxy)-N-(methylsulf onyl)-2-nitro-
CAS REGISTRY NUMBER :
72178-02-0
LAST UPDATED :
199710
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C15-H10-Cl-F3-N2-O6-S
MOLECULAR WEIGHT :
438.78

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,433,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,433,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,433,1991

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S2

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
CV2475000

[ HS Code ]:
2935009016

Synthetic Route

Precursor & DownStream

Precursor

  • 3-(2-chloro-α,α,α-trifluoro-4-tolyloxy)-N-(methylsulphonyl)benzamide
  • Methanesulfonamide
  • Acifluorfen

DownStream

Customs

[ HS Code ]: 2935009016

[ Summary ]:
2935009016 methyl (4-aminophenyl)sulfonylcarbamate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:35.0%

Articles

The effect of protoporphyrinogen oxidase inhibitors on microsomal and mitochondrial cytochromes.

Obes. Res. 3 Suppl 5 , 785S-788S, (1995)

Neurological dysfunction is a characteristic feature of acute porphyrias, unexplained until now. One of the possible explanations is a deficiency of heme in the central nervous system, caused by a blo...

Occurrence and distribution of sulfonylurea and related herbicides in central Canadian surface waters 2006-2008.

Bull. Environ. Contam. Toxicol. 87(4) , 420-5, (2011)

Surface water sampling in 2006-2008 measured the occurrence of sulfonylureas and related herbicides (SUs) during base flow conditions and wet weather events. Flumetsulam (29.2%), diuron (36.5%) and fo...

Experimental hepatic uroporphyria induced by the diphenyl-ether herbicide fomesafen in male DBA/2 mice.

Toxicol. Appl. Pharmacol. 189(1) , 28-38, (2003)

Hepatic uroporphyria can be readily induced by a variety of treatments in mice of the C57BL strains, whereas DBA/2 mice are almost completely resistant. However, feeding of the protoporphyrinogen oxid...


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Related Compounds

  • fomesafen-sodium
  • FOMESAFEN,ACIDFORM
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 5-Formylthiazole-2-carbonitrile
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 4-Chloro-2-{[trans-2-hydroxycyclobutyl]amino}phenol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 2-(Benzylsulfanyl)thieno[3,2-d]pyrimidin-4-ol
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde