N,N-diethyl-N'-(9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-1-yl)propane-1,3-diamine

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Names

[ CAS No. ]:
72238-02-9

[ Name ]:
N,N-diethyl-N'-(9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-1-yl)propane-1,3-diamine

[Synonym ]:
1-((3-(Diethylamino)propyl)amino)-5,11-dimethyl-9-methoxy-6H-pyrido(4,3-b)carbazole
Reteliptina [Spanish]
Petelliptine [French]
BD-84
1-<<3-(diethylamino)propyl>amino>-5,11-dimethyl-6H-pyrido<4,3-b>carbazole
Retelliptine
6H-Pyrido(4,3-b)carbazole,1-((3-diethylamino)propylamino)-5,11-dimethyl-9-methoxy
N,N-diethyl-N'-(9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-1-yl)-propane-1,3-diamine
Retelliptinum [Latin]
1-((3-(Diethylamino)propyl)amino)-9-methoxy-5,11-dimethyl-6H-pyrido(4,3-b)carbazole

Chemical & Physical Properties

[ Density]:
1.17g/cm3

[ Boiling Point ]:
626.8ºC at 760 mmHg

[ Molecular Formula ]:
C25H32N4O

[ Molecular Weight ]:
404.54800

[ Flash Point ]:
332.9ºC

[ Exact Mass ]:
404.25800

[ PSA ]:
53.18000

[ LogP ]:
5.71150

[ Index of Refraction ]:
1.674

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TX7387000
CHEMICAL NAME :
1,3-Propanediamine, N,N-diethyl-N'-(9-methoxy-5,11-dimethyl-6H-pyrido(4,3 -b)carbazol-1-yl)-
CAS REGISTRY NUMBER :
72238-02-9
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C25-H32-N4-O
MOLECULAR WEIGHT :
404.61
WISWESSER LINE NOTATION :
T D6 B656 FN LMJ C1 EM3N2&2 J1 PO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
60 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,181,1983
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
60 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1212,1980

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-chloro-9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole
  • N,N-Diethylpropan-1,3-diamin

DownStream

Related Compounds

  • 1-Amino-2-cyclobutyl-propan-2-ol hydrochloride
  • Methyl 4-(methylamino)thieno[2,3-d]pyrimidine-6-carboxylate
  • (1-Benzylpiperidin-4-yl)-[2-(5-methoxy-2-nitrophenyl)-ethyl]-amine
  • 5-Methoxy-2,2-dimethylpentanal
  • Azetidine-3-carbaldehyde
  • Propanedioic acid, 2-[2-[4-(trifluoromethyl)phenyl]hydrazinylidene]-, 1,3-dimethyl ester
  • 1-(3,7-Dimethylocta-2,6-diene-1-sulfonyl)-4-methylbenzene
  • 3-(1H-imidazo[4,5-c]pyridin-2-yl)aniline
  • N-(3-amino-4-chlorophenyl)morpholine-4-sulfonamide
  • 3-(4-(morpholin-4-yl)phenyl)-2-phenylquinazolin-4(3H)-one