3-Amino-1-methyl-5H-pyrido(4,3-b)indole

Suppliers

Names

[ CAS No. ]:
72254-58-1

[ Name ]:
3-Amino-1-methyl-5H-pyrido(4,3-b)indole

[Synonym ]:
3-amino-1-methyl-5H-pyrido<4,3-b>indole-acetate salt
1,4-Dimethyl-5H-pyrido[4,3-b]indol-3-amine Monoacetate
acetic acid salt of 3-amino-1,4-dimethyl-5H-pyrido<4,3-b>indole
Trp-P-2 acetate
Tryptophan p 1 acetate
3-b)indole,3-amino-1,4-dimethyl-5h-pyrido(acetate
Tryptophan p 2 acetate
3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole acetate salt
3-b)indol-3-amine,1,4-dimethyl-5h-pyrido(monoacetate
3-Amino-1-methyl-5H-pyrido[4,3-b]indole acetate
3-b)indol-3-amine,1,4-dimethyl-5h-pyrido(acetate
Trp-P-1 acetate
acetic acid salt of 3-amino-1-methyl-5H-pyrido<4,3-b>indole
1-methyl-5H-pyrido[4,3-b]indol-3-ylammonium acetate
3-Amino-1-methyl-5H-pyrido<4,3-b>indol-Acetat

Chemical & Physical Properties

[ Density]:
1.334g/cm3

[ Boiling Point ]:
455.7ºC at 760 mmHg

[ Melting Point ]:
>300ºC

[ Molecular Formula ]:
C12H11N3

[ Molecular Weight ]:
197.23600

[ Flash Point ]:
260.1ºC

[ Exact Mass ]:
197.09500

[ PSA ]:
54.70000

[ LogP ]:
3.18790

[ Index of Refraction ]:
1.806

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU9355000
CHEMICAL NAME :
5H-Pyrido(4,3-b)indole, 3-amino-1-methyl-, acetate
CAS REGISTRY NUMBER :
72254-58-1
LAST UPDATED :
199806
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C12-H11-N3.C2-H4-O2
MOLECULAR WEIGHT :
257.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3011 mg/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
14 gm/kg/89W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors
TYPE OF TEST :
Specific locus test
TYPE OF TEST :
Sister chromatid exchange
TYPE OF TEST :
Micronucleus test

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
13 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 395,57,1997

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl 2-(cyanomethyl)indole-1-carboxylate
  • 1(2H)-Quinolinecarboxylicacid, 2-cyano-, ethyl ester
  • 1-(Phenylsulfonyl)-1H-indole
  • 2-(1H-indol-2-ylmethylidene)propanedioic acid
  • (E)-methyl 3-(1H-indol-2-yl)acrylate
  • (E)-3-(1H-indol-2-yl)acrylic acid
  • methyl 1-methyl-5H-pyrido[4,3-b]indole-3-carboxylate

DownStream

  • N-(1-methyl-5H-pyrido[4,3-b]indol-3-yl)acetamide
  • 3-hydroxyamino-1-methyl-5H-pyrido(4,3-b)indole
  • 3-Nitro-1-Methyl-5H-pyrido[4,3-b]indole

Related Compounds

  • 3-AMINO-1-METHYL-5H-PYRIDO[4,3-B] INDOLE ACETATE
  • 3-Amino-4-ethyl-1-methyl-5H-pyrido(4,3-b)indole acetate
  • 3-Amino-1-propyl-5H-pyrido(4,3-b)indole acetate
  • 3-hydroxyamino-1-methyl-5H-pyrido(4,3-b)indole
  • 3-Nitro-1-Methyl-5H-pyrido[4,3-b]indole
  • 3-AMINO-1,4-DIMETHYL-5H-PYRIDO[4,3-B]INDOLE, ACETATE
  • Ethanol, 2,2'-[1,3-propanediylbis(sulfonyl)]bis-
  • 3-Chloro-1-(morpholinyl)-1-ylisoquinoline
  • (3-Chlorophenyl)(tetrahydro-1H-furo[3,4-c]pyrrol-5(3H)-yl)methanone
  • 2-Chloro-4-(difluoromethyl)aniline
  • N-hydroxy-2-methoxynaphthalene-1-carboxamide
  • 2-(2-Thienyl)oxazolidine
  • Phenanthrene-9-sulfonyl chloride
  • Ethyl 2-amino-2-(pyridin-4-yl)acetate hydrochloride
  • (3S,4S)-3-(tert-Butoxycarbonyl)amino-4-cyclopropylpyrrolidine
  • Pravastatin Methyl Ester
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.