1-Triazene,3,3-dimethyl-1-(4-nitrophenyl)-

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Names

[ CAS No. ]:
7227-92-1

[ Name ]:
1-Triazene,3,3-dimethyl-1-(4-nitrophenyl)-

[Synonym ]:
1-(p-nitrophenyl)-3,3-dimethyltriazene
1-(4-Nitrophenyl)-3,3-dimethyltriazene
Triazene,3,3-dimethyl-1-(p-nitrophenyl)
3,3-dimethyl-1-(p-nitrophenyl)-1-triazene
1-(p-nitrophenyl)-3,3-dimethyl-1-triazene
1-p-Nitrofenyl-3,3-dimethyltriazen
3,3-dimethyl-1-(4-nitrophenyl)triazene
3,3-Dimethyl-1-(p-nitrophenyl)triazene
3,3-Dimethyl-1-(4-nitro-phenyl)-triazen
1-(p-Nitrophenyl)-3,3-dimethyltriazine
3,3-Dimethyl-p-nitrophenyltriazene

Chemical & Physical Properties

[ Molecular Formula ]:
C8H10N4O2

[ Molecular Weight ]:
194.19100

[ Exact Mass ]:
194.08000

[ PSA ]:
73.78000

[ LogP ]:
2.67830

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XY1450000
CHEMICAL NAME :
Triazene, 3,3-dimethyl-1-(p-nitrophenyl)-
CAS REGISTRY NUMBER :
7227-92-1
LAST UPDATED :
199410
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C8-H10-N4-O2
MOLECULAR WEIGHT :
194.22
WISWESSER LINE NOTATION :
WNR DNUNN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1664 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Gastrointestinal - ulceration or bleeding from stomach Liver - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3250 mg/kg/72W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Brain and Coverings - tumors Peripheral Nerve and Sensation - peripheral nerve tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
330 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Peripheral Nerve and Sensation - peripheral nerve tumors

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
1 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 190,183,1987

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Nitroaniline
  • Dimethylamine
  • 4-Nitrophenyldiazonium tetrafluoroborate
  • N,N-Dimethylformamide
  • 4-nitrobenzenediazonium chloride

DownStream

  • 5-Nitro-2-phenylpyridine
  • 3-(4-nitrophenyl)pyridine
  • 4-Chloronitrobenzene
  • 1-Bromo-4-nitrobenzene
  • pnb
  • 1-Iodo-4-nitrobenzene
  • 4-nitrobenzenediazonium
  • Dimethylamine
  • 1-(4-chlorobut-2-enylsulfonyl)-4-nitrobenzene

Related Compounds

  • 1-Triazene,3,3-dimethyl-1-(2-methyl-4-nitrophenyl)-
  • 1-Triazene,3,3-dimethyl-1-(4-methylphenyl)-
  • 1-Triazene,3,3-dimethyl-1-[4-nitro-3-(trifluoromethyl)phenyl]-
  • N-methyl-N-[(4-phenyldiazenylphenyl)diazenyl]methanamine
  • N-methyl-N-[(4-methylsulfanylphenyl)diazenyl]methanamine
  • 1-Triazene,3,3-dimethyl-1-(2,4,6-trimethylphenyl)-
  • Benzyl 2-(2,4-dimethyl-1,3-dioxo-7-phenyl-4a,9a-dihydropurino[7,8-a]imidazol-6-yl)acetate
  • 6-(4-Fluorophenyl)-2-hexyl-4-methyl-4a,7,8,9a-tetrahydropurino[7,8-a]imidazole-1,3-dione
  • 1-(2-ethoxyethyl)-3,9-dimethyl-7-(naphthalen-1-ylmethyl)-5a,9a,10,10a-tetrahydro-4H-purino[8,7-c][1,2,4]triazine-6,8-dione
  • 2-[(4-Fluorophenyl)methyl]-6-(2-hydroxyphenyl)-4,7-dimethyl-4a,9a-dihydropurino[7,8-a]imidazole-1,3-dione
  • 1-[(4-fluorophenyl)methyl]-3,4,9-trimethyl-7-(2-methylprop-2-enyl)-5a,9a,10,10a-tetrahydro-4H-purino[8,7-c][1,2,4]triazine-6,8-dione
  • 1-benzyl-7-[(4-fluorophenyl)methyl]-3,9-dimethyl-5a,9a,10,10a-tetrahydro-4H-purino[8,7-c][1,2,4]triazine-6,8-dione
  • 3,9-dimethyl-1-[(4-methylphenyl)methyl]-7-(2-methylprop-2-enyl)-5a,9a,10,10a-tetrahydro-4H-purino[8,7-c][1,2,4]triazine-6,8-dione
  • L-Glutaminyl-L-valyl-L-leucyl-L-histidyl-L-threonyl-L-seryl-L-asparagine
  • 1-[(2S,4S)-4-tert-Butyl-2-methoxypiperidin-1-yl]-2,2,2-trifluoroethan-1-one
  • N~5~-(Diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-L-lysyl-L-threonyl-L-leucyl-L-leucine
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