Streptolydigin

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Names

[ CAS No. ]:
7229-50-7

[ Name ]:
Streptolydigin

[Synonym ]:
Antibiotic D-45
portamycin
Streptolydigin
2-Pyrrolidineacetamide, 4-[6-(1,4-dimethylspiro[2,9-dioxabicyclo[3.3.1]non-6-ene-8,2'-oxiran-3-yl)-1-hydroxy-4-methyl-2,4-heptadienylidene]-N,.α.-dimethyl-3,5-dioxo-1-(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-

Chemical & Physical Properties

[ Density]:
1.3 g/cm3

[ Boiling Point ]:
826.6ºC at 760 mmHg

[ Molecular Formula ]:
C32H44N2O9

[ Molecular Weight ]:
600.70000

[ Flash Point ]:
453.7ºC

[ Exact Mass ]:
600.30500

[ PSA ]:
147.16000

[ LogP ]:
2.78890

[ Index of Refraction ]:
1.598

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WK4250000
CHEMICAL NAME :
Streptolydigin
CAS REGISTRY NUMBER :
7229-50-7
LAST UPDATED :
199403
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C32-H44-N2-O9
MOLECULAR WEIGHT :
600.78

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
533 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Bacteria - Bacillus subtilis
DOSE/DURATION :
288 mg/L
REFERENCE :
FOMIAZ Folia Microbiologica (Prague). (Academia, Vodickova 40, 112 29 Prague 1, Czechoslavakia) V.4- 1959- Volume(issue)/page/year: 22,329,1977

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

  • 4-Methyl-3-[(7-methyl-2,7-diazaspiro[4.4]non-2-yl)methyl]benzenamine
  • 3-(4-Chlorophenoxy)-2-methyl-5-(trifluoromethyl)-1H-indole
  • 1-(5-Amino-3-methyl-2-pyridinyl)-3,3-dimethyl-2-piperazinone
  • Tert-butyl 4-((4-aminopyridin-2-yl)methyl)-3-oxopiperazine-1-carboxylate
  • 4-Methyl-3-(4h-1,2,4-triazol-4-ylmethyl)benzenamine
  • 3-[(4-Cyclopropyl-1-piperazinyl)methyl]-4-methylbenzenamine
  • Tert-butyl 4-((4-aminopyridin-2-yl)methyl)piperazine-1-carboxylate
  • 3-amino-N-tert-butyl-5-fluorobenzenesulfonamide
  • tert-butyl N-[1-(2,4-dichlorophenyl)-1-hydroxypropan-2-yl]carbamate
  • 6-Fluoro-4-oxo-7-(pyrrolidin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
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