Streptolydigin

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Names

[ CAS No. ]:
7229-50-7

[ Name ]:
Streptolydigin

[Synonym ]:
Antibiotic D-45
portamycin
Streptolydigin
2-Pyrrolidineacetamide, 4-[6-(1,4-dimethylspiro[2,9-dioxabicyclo[3.3.1]non-6-ene-8,2'-oxiran-3-yl)-1-hydroxy-4-methyl-2,4-heptadienylidene]-N,.α.-dimethyl-3,5-dioxo-1-(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-

Chemical & Physical Properties

[ Density]:
1.3 g/cm3

[ Boiling Point ]:
826.6ºC at 760 mmHg

[ Molecular Formula ]:
C32H44N2O9

[ Molecular Weight ]:
600.70000

[ Flash Point ]:
453.7ºC

[ Exact Mass ]:
600.30500

[ PSA ]:
147.16000

[ LogP ]:
2.78890

[ Index of Refraction ]:
1.598

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WK4250000
CHEMICAL NAME :
Streptolydigin
CAS REGISTRY NUMBER :
7229-50-7
LAST UPDATED :
199403
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C32-H44-N2-O9
MOLECULAR WEIGHT :
600.78

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
533 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Bacteria - Bacillus subtilis
DOSE/DURATION :
288 mg/L
REFERENCE :
FOMIAZ Folia Microbiologica (Prague). (Academia, Vodickova 40, 112 29 Prague 1, Czechoslavakia) V.4- 1959- Volume(issue)/page/year: 22,329,1977

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

  • 2-(2-Chloro-3-methylphenyl)-2-methylpropan-1-amine
  • 3-Amino-1-(2-methylsulfonylethyl)pyrazole-4-carbonitrile
  • 1-(3-Chloro-4-fluorophenyl)ethane-1,2-diol
  • Cyclopentane-1,3-diamine hydrochloride
  • 4-(4-Chloro-2-hydroxyphenyl)butan-2-one
  • 2-(Methylthio)-6,7-dihydro-5H-cyclopenta[d]pyrimidine-5-carboxylic acid
  • N-(2-Nitrophenyl)-N-propylmethanesulfonamide
  • 3-(2-(Trifluoromethyl)-1h-imidazol-1-yl)propan-1-amine
  • 3-amino-1-(1-methyl-1H-pyrazol-4-yl)propan-1-one
  • 2-(4-amino-3,5-diethyl-1H-pyrazol-1-yl)acetamide
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