1-phenylisatin

Suppliers

Names

[ CAS No. ]:
723-89-7

[ Name ]:
1-phenylisatin

[Synonym ]:
n-phenylisatin
1-Phenylisatin
MFCD00082681
1H-Indole-2,3-dione,1-phenyl
1-Phenyl-indole-2,3-dione
INDOLE-2,3-DIONE,1-PHENYL
1-Phenylindoline-2,3-dione
N-phenylindoline-2,3-dione

Chemical & Physical Properties

[ Density]:
1.338g/cm3

[ Boiling Point ]:
388.8ºC at 760 mmHg

[ Melting Point ]:
138-140 °C(lit.)

[ Molecular Formula ]:
C14H9NO2

[ Molecular Weight ]:
223.22700

[ Flash Point ]:
182.6ºC

[ Exact Mass ]:
223.06300

[ PSA ]:
37.38000

[ LogP ]:
2.61260

[ Index of Refraction ]:
1.667

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NL7984000
CHEMICAL NAME :
Indole-2,3-dione, 1-phenyl-
CAS REGISTRY NUMBER :
723-89-7
BEILSTEIN REFERENCE NO. :
0164531
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H9-N-O2
MOLECULAR WEIGHT :
223.24
WISWESSER LINE NOTATION :
T56 BNVVJ BR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
425 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,858,1981

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Precautionary Statements ]:
P301 + P312 + P330

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R23/24/25

[ Safety Phrases ]:
S27-S28-S36/37/39-S45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
NL7984000

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • isatin
  • Phenylboronic acid
  • 1-(2-(Phenylamino)phenyl)ethanone
  • phenylindole
  • Oxalyl chloride
  • Diphenylamine
  • (N,N-diphenylcarbamoyl) formyl chloride
  • 2-(2-bromophenyl)-N-phenylacetamide
  • N-Phenylamide of ethanedioic acid methyl ester
  • 2-trimethylsilylphenyl triflate

DownStream

  • Linopirdine(DuP-996)
  • 9-Acridinecarboxylic acid
  • Acridone
  • 1-Phenyloxindole
  • Methyl acridine-9-carboxylate
  • methyl 10-methylacridine-9-carboxylate; sulfooxymethane
  • 1-PHENYL-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE
  • HT-2157
  • 2-Anilino phenylacetic Acid
  • 1,3,3-triphenylindol-2-one

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Unraveling the binding interaction and kinetics of a prospective anti-HIV drug with a model transport protein: results and challenges.

Phys. Chem. Chem. Phys. 15(4) , 1275-87, (2013)

The present contribution reports a detailed characterization of the binding interaction of a potential anticancer, anti-HIV drug 1-phenylisatin (1-PI) with a model transport protein Bovine Serum Album...

Fluorescence spectroscopic characterization of the interaction of human adult hemoglobin and two isatins, 1-methylisatin and 1-phenylisatin: a comparative study.

J. Phys. Chem. B 113(45) , 14904-13, (2009)

In this report, steady state and time-resolved fluorescence along with circular dichroism (CD) spectroscopic, FTIR, and anisotropy investigations were made to reveal the nature of the interactions bet...


More Articles

Related Compounds

  • 1-phenyl-3H-[1,2,4]triazolo[4,3-a]quinazolin-5-one
  • 1-[2-(2-fluorobenzoyl)pyrrol-1-yl]propan-2-yl-dimethylazanium,chloride
  • 1-[4-Amino-3-chloro-5-(trifluoromethyl)phenyl]-2-bromo-ethanone
  • 1,4-BenzenediaMine, N,N,N',N'-tetrakis[4-[bis(2-Methylpropyl)aMino]phenyl]-
  • 1-[2-(2-methoxybenzoyl)pyrrol-1-yl]propan-2-yl-dimethylazanium,chloride
  • 1-(4-Amino-3,5-dichloro-phenyl)-2-tert-butylamino-ethanone Hydrochloride
  • 2,5-Dioxopyrrolidin-1-yl 1-methyl-1H-pyrazole-4-carboxylate
  • 2,5-Dioxopyrrolidin-1-yl 5-chlorobenzofuran-2-carboxylate
  • rel-(3aR,4S,6aS)-Hexahydro-cyclopenta[c]furan-4-ol
  • 3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester
  • 1-Fluoro-cyclopropanecarboxylic acid benzyl ester
  • 2,2,2-Trifluoro-1-(4-fluoro-2-hydroxy-phenyl)-ethanone
  • 1-(4-Amino-3-chloro-phenyl)-2,2,2-trifluoro-ethanone
  • [3-(2-Bromo-acetyl)-phenyl]-carbamic acid tert-butyl ester
  • (2S,3S)-2-Amino-3-(4-hydroxy-phenyl)-butyric acid ethyl ester
  • (R)-3-Benzyloxycarbonylamino-2-(trityl-amino)-propionic acid methyl ester
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.