2-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-4-propoxy-pyrimidine-5-carb oxamide

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Names

[ CAS No. ]:
72418-31-6

[ Name ]:
2-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-4-propoxy-pyrimidine-5-carb oxamide

Chemical & Physical Properties

[ Density]:
1.143g/cm3

[ Molecular Formula ]:
C15H25N5O2

[ Molecular Weight ]:
307.39100

[ Exact Mass ]:
307.20100

[ PSA ]:
93.37000

[ LogP ]:
1.97170

[ Index of Refraction ]:
1.549

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV7704600
CHEMICAL NAME :
5-Pyrimidinecarboxamide, 2-amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-4-propoxy-
CAS REGISTRY NUMBER :
72418-31-6
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C15-H25-N5-O2
MOLECULAR WEIGHT :
307.45
WISWESSER LINE NOTATION :
T6N CNJ BZ DO3 EVM1- BT5NTJ A2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 17,437,1982

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • propyl 2-amino-4-propoxypyrimidine-5-carboxylate
  • 2-(Aminomethyl)-1-ethylpyrrolidine
  • 2-amino-4-propoxypyrimidine-5-carboxylic acid

DownStream

Related Compounds

  • 2-[3-(4-Bromophenyl)-1-nitrosoazetidin-3-yl]acetic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 3-chloro-5-nitro-2-[4-(3-oxetanyl)-2H-1,2,3-triazol-2-yl]Pyridine