Psora-4

Suppliers

Names

[ CAS No. ]:
724709-68-6

[ Name ]:
Psora-4

[Synonym ]:
Lopac-P-9872
5-(4-Phenylbutoxy)psoralen
Psora-4

Chemical & Physical Properties

[ Density]:
1.246g/cm3

[ Boiling Point ]:
537.7ºC at 760 mmHg

[ Molecular Formula ]:
C₂₁H₁₈O₄

[ Molecular Weight ]:
334.36500

[ Flash Point ]:
279ºC

[ Exact Mass ]:
334.12100

[ PSA ]:
52.58000

[ LogP ]:
4.94090

[ Index of Refraction ]:
1.626

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335-H413

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
C

[ RIDADR ]:
NONH for all modes of transport

Articles

Psora-4, a Kv1.3 Blocker, Enhances Differentiation and Maturation in Neural Progenitor Cells.

CNS Neurosci. Ther. 21 , 558-67, (2015)

The self-repair ability of neural progenitor cells (NPCs) has been found to be activated and protected in several therapies helpful in multiple sclerosis (MS), an inflammatory demyelinating disease of...

K+ channels as targets for specific immunomodulation.

Trends Pharmacol. Sci. 25 , 280-289, (2004)

The voltage-gated Kv1.3 channel and the Ca(2+)-activated IKCa1 K(+) channel are expressed in T cells in a distinct pattern that depends on the state of lymphocyte activation and differentiation. The c...

Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators.

Mol. Pharmacol. 65 , 1364-1374, (2004)

The lymphocyte potassium channel Kv1.3 is widely regarded as a promising new target for immunosuppression. To identify a potent small-molecule Kv1.3 blocker, we synthesized a series of 5-phenylalkoxyp...

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