STF 31

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Names

[ Name ]:
STF 31

[Synonym ]:
Benzamide, 4-[[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinyl-
4-[({[4-(2-Methyl-2-propanyl)phenyl]sulfonyl}amino)methyl]-N-(3-pyridinyl)benzamide
2HJ
4-({[(4-Tert-Butylphenyl)sulfonyl]amino}methyl)-N-(Pyridin-3-Yl)benzamide
4-((4-tert-butylphenylsulfonamido)methyl)-N-(pyridin-3-yl)benzamide
QC-5204
STF-31

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Molecular Formula ]:
C₂₃H₂₅N₃O₃S

[ Molecular Weight ]:
423.528

[ Exact Mass ]:
423.161652

[ PSA ]:
96.54000

[ LogP ]:
3.88

[ Index of Refraction ]:
1.612

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ RIDADR ]:
NONH for all modes of transport

Articles

A novel effect of DMOG on cell metabolism: direct inhibition of mitochondrial function precedes HIF target gene expression.

Biochim. Biophys. Acta 1847 , 1254-66, (2015)

Abnormal accumulation of oncometabolite fumarate and succinate is associated with inhibition of mitochondrial function and carcinogenesis. By competing with α-ketoglutarate, oncometabolites also activ...

NAMPT is the cellular target of STF-31-like small-molecule probes.

ACS Chem. Biol. 9(10) , 2247-54, (2014)

The small-molecule probes STF-31 and its analogue compound 146 were discovered while searching for compounds that kill VHL-deficient renal cell carcinoma cell lines selectively and have been reported ...

Glucose is a key driver for GLUT1-mediated nanoparticles internalization in breast cancer cells.

Sci. Rep. 6 , 21629, (2016)

The mesenchymal state in cancer is usually associated with poor prognosis due to the metastatic predisposition and the hyper-activated metabolism. Exploiting cell glucose metabolism we propose a new m...