(R)-pyrrolidine-3-carboxylic acid

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Names

[ CAS No. ]:
72580-54-2

[ Name ]:
(R)-pyrrolidine-3-carboxylic acid

[Synonym ]:
3-Pyrrolidinecarboxylic acid
(S)-Pyrrolidine-3-carboxylic acid
Pyrrolidine-3-carboxylic acid
UNII:XQ9918NB1D
MFCD06738463
(R)-pyrrolidine-3-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
252.2±33.0 °C at 760 mmHg

[ Molecular Formula ]:
C5H9NO2

[ Molecular Weight ]:
115.131

[ Flash Point ]:
106.3±25.4 °C

[ Exact Mass ]:
115.063332

[ PSA ]:
49.33000

[ LogP ]:
-0.47

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.487

[ Storage condition ]:
2-8°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2942000000

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Diastereocontrolled synthesis of enantioenriched 3,4-disubstituted beta-prolines.

J. Org. Chem. 72 , 398, (2007)

Enantioenriched 3,4-disubstituted beta-prolines have been prepared with a high diastereocontrol through a carbometalation reaction or through a domino Michael addition/carbometalation reaction.

Beta-proline analogues as agonists at the strychnine-sensitive glycine receptor.

J. Med. Chem. 35 , 233, (1992)

3-Carboxy-3,4-dehydropyrrolidine was found to bind with affinity equal to that of glycine in a [3H]strychnine binding assay. Simple substitution of the 1-, 2-, 4-, or 5-position resulted in marked los...

Endomorphin-1 analogues containing beta-proline are mu-opioid receptor agonists and display enhanced enzymatic hydrolysis resistance.

J. Med. Chem. 45(12) , 2571-8, (2002)

In this paper we describe the synthesis and affinity toward the mu-opioid receptor of some tetrapeptides obtained from endomorphin-1, H-Tyr-Pro-Trp-Phe-NH(2) (1), by substituting each amino acid in tu...


More Articles


Related Compounds

  • (R)-PYRROLIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
  • (R)-Methyl pyrrolidine-3-carboxylate hydrochloride
  • (R)-1-BENZYL-PYRROLIDINE-3-CARBOXYLIC ACID
  • (R)-1-BENZYL-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID
  • (R)-3-amino-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid
  • Methyl1-benzyl-3-(trifluoromethyl)pyrrolidine-3-carboxylate