miglustat

Suppliers

Names

[ Name ]:
miglustat

[Synonym ]:
nojirimycin, N-butyldeoxy-
Butyldeoxynojirimycin
N-Butyldeoxynojirimycin
N-Butyl-deoxynojirimycin
1,5-(BUTYLIMINO)-1,5-DIDEOXY-D-GLUCITOL
N-Butylmoranoline
(2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)-3,4,5-piperidinetriol
(2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol
MFCD00272581
N-(n-Butyl)deoxynojirimycin
BuDNJ
NB-DNJ
3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, (2R,3R,4R,5S)-
miglustat
N-butyl-1-deoxynojirimycin
n-Butyl deoxynojirimycin
Zavesca
n-Butyl dnj

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
394.7±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₂₁NO₄

[ Molecular Weight ]:
219.278

[ Flash Point ]:
215.4±26.5 °C

[ Exact Mass ]:
219.147064

[ PSA ]:
84.16000

[ LogP ]:
0.46

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.546

[ Storage condition ]:
2-8℃

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1-Deoxynojirimycin
Butyraldehyde
1-Bromobutane
TRIMETHYLACETIC ANHYDRIDE
1,2-O-Isopropylidene-5-keto-α-D-glucose
1,2-O-Isopropylidene-a-D-glucofuranose
2,3,4,6-Tetra-O-benzyl-D-glucopyranose
(2R,3R,4S)-2,3,4,6-tetrakis(benzyloxy)-5-oxohexanal

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Development of a cell-based hepatitis C virus infection fluorescent resonance energy transfer assay for high-throughput antiviral compound screening.

Antimicrob. Agents Chemother. 53(10) , 4311-9, (2009)

A major obstacle in the treatment of chronic hepatitis C virus (HCV) infection has been the lack of effective, well-tolerated therapeutics. Notably, the recent development of the HCV cell culture infe...

Inhibitors of the tick-borne, hemorrhagic fever-associated flaviviruses.

Antimicrob. Agents Chemother. 58(6) , 3206-16, (2014)

No antiviral therapies are available for the tick-borne flaviviruses associated with hemorrhagic fevers: Kyasanur Forest disease virus (KFDV), both classical and the Alkhurma hemorrhagic fever virus (...

Modulation of hepatitis C virus genome replication by glycosphingolipids and four-phosphate adaptor protein 2.

J. Virol. 88(21) , 12276-95, (2014)

Hepatitis C virus (HCV) assembles its replication complex on cytosolic membrane vesicles often clustered in a membranous web (MW). During infection, HCV NS5A protein activates PI4KIIIα enzyme, causing...