Benzyl (S)-4-oxo-2-azetidinecarboxylate

Names

[ CAS No. ]:
72776-05-7

[ Name ]:
Benzyl (S)-4-oxo-2-azetidinecarboxylate

[Synonym ]:
benzyl (2S)-4-oxoazetidine-2-carboxylate
MFCD00798164

Chemical & Physical Properties

[ Density]:
1.268 g/cm3

[ Boiling Point ]:
404.7ºC at 760 mmHg

[ Melting Point ]:
137-140ºC(lit.)

[ Molecular Formula ]:
C₁₁H₁₁NO₃

[ Molecular Weight ]:
205.21000

[ Flash Point ]:
198.5ºC

[ Exact Mass ]:
205.07400

[ PSA ]:
55.40000

[ LogP ]:
0.94710

[ Index of Refraction ]:
1.565

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933790090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Articles

Orally active beta-lactam inhibitors of human leukocyte elastase. 3. Stereospecific synthesis and structure-activity relationships for 3,3-dialkylazetidin-2-ones.

J. Med. Chem. 38 , 2449, (1995)

The stereospecific synthesis of several 4-[(4-carboxyphenyl)oxy]- 3,3-dialkyl-1-[[(1-phenylalkyl)-amino]carbonyl]azetidin-2-on es 3 is described in which the C-3 alkyl groups were varied from methyl t...

Baldwin, J.E. et al.

Tetrahedron 51 , 11581, (1995)

Hanessian, S. et al.

Synlett , 33, (1992)

benzyl (S)-[4-[(aminocarbonyl)amino]-1-[[(4-nitrophenyl)amino]carbonyl]butyl]carbamate
benzyl ((1S,2R)-2-methyl-1-((S)-4-oxo-2-propyl-3,4-dihydropyridin-1(2H)-yl)butyl)carbamate
benzyl 4-oxo-2-(phenylmethoxycarbonylamino)butanoate
BENZYL 4-OXO-2-PHENYL-3,4-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE
benzyl 4-oxo-2-(trifluoromethyl)piperidine-1-carboxylate
BENZYL 4-OXO-2-PROPYL-3,4-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE
2-(thiophen-2-yl)-N-((2-(thiophen-3-yl)pyridin-4-yl)methyl)acetamide
4-methyl-N-((2-(thiophen-3-yl)pyridin-4-yl)methyl)-1,2,3-thiadiazole-5-carboxamide
3-cyano-N-((2-(thiophen-3-yl)pyridin-4-yl)methyl)benzamide
1-methyl-2-oxo-N-((2-(thiophen-3-yl)pyridin-4-yl)methyl)-1,2-dihydropyridine-3-carboxamide
2-(4-fluorophenyl)-N-((2-(thiophen-3-yl)pyridin-4-yl)methyl)acetamide
(E)-3-(thiophen-2-yl)-N-((2-(thiophen-3-yl)pyridin-4-yl)methyl)acrylamide
3,4-difluoro-N-((2-(thiophen-3-yl)pyridin-4-yl)methyl)benzamide
5-chloro-N-((2-(thiophen-3-yl)pyridin-4-yl)methyl)thiophene-2-carboxamide
3-(dimethylamino)-N-((2-(thiophen-3-yl)pyridin-4-yl)methyl)benzamide
N-((2-(thiophen-3-yl)pyridin-4-yl)methyl)benzo[d][1,3]dioxole-5-carboxamide

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