Quinethazone

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Names

[ CAS No. ]:
73-49-4

[ Name ]:
Quinethazone

[Synonym ]:
Quimethazin
Quinethazonum
Hydromox
Quinetazona
Quinethazon
Chinethazonum
7-Chlor-6-sulfamoyl-2-aethyl-4-oxo-1,2,3,4-tetrahydro-chinazolin
UNII:455E0S048W
6-Quinazolinesulfonamide, 7-chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-
7-Chlor-2-aethyl-6-sulfamoyl-1,2,3,4-tetrahydro-4-chinazolinon
quinethazone
7-chloro-2-ethyl-4-oxo-1,2,3,4-tetrahydro-quinazoline-6-sulfonic acid amide
7-chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-6-quinazolinesulfonamide
Aquamox
7-Chloro-2-ethyl-4-oxo-1,2,3,4-tetrahydro-6-quinazolinesulfonamide
7-Chloro-2-ethyl-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
Idrokin

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Melting Point ]:
250 - 252ºC

[ Molecular Formula ]:
C10H12ClN3O3S

[ Molecular Weight ]:
289.739

[ Exact Mass ]:
289.028778

[ PSA ]:
109.67000

[ LogP ]:
0.49

[ Index of Refraction ]:
1.582

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA1679500
CHEMICAL NAME :
6-Quinazolinesulfonamide, 1,2,3,4-tetrahydro-7-chloro-2-ethyl-4-oxo-
CAS REGISTRY NUMBER :
73-49-4
BEILSTEIN REFERENCE NO. :
0818554
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H12-Cl-N3-O3-S
MOLECULAR WEIGHT :
289.76

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,201,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5486 No. of Facilities: 16 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 94 (estimated) No. of Female Employees: 62 (estimated)

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

  • QUINETHAZONE
  • Quinethazone-d5
  • 4-{5-[2-(4-Chloro-phenoxy)-ethyl]-4-methyl-thiazol-2-yl}-azepan-4-ol hydrochloride
  • (1-Phenethyl-piperidin-4-yl)-acetic acid hydrochloride
  • 4-{5-[2-(2-Chloro-phenoxy)-ethyl]-4-methyl-thiazol-2-yl}-azepan-4-ol hydrochloride
  • (4-(5-(5-Methylpyrazin-2-yl)-1,3,4-oxadiazol-2-yl)cyclohexyl)methanamine hydrochloride
  • (1-Cyclohexyl-piperidin-4-yl)-acetic acid hydrochloride
  • (5-Methyl-thiazol-2-yl)-(6-pyrrolidin-2-yl-pyridin-2-yl)-amine hydrochloride
  • 4-Methyl-2-(pyrrolidin-2-yl)-6-(trifluoromethyl)pyrimidine hydrochloride
  • 2-Methyl-4-(3-methylpiperidin-3-yl)pyrimidine dihydrochloride
  • (6-Piperidin-4-yl-pyrazin-2-yl)-pyrimidin-2-yl-amine hydrochloride
  • N-(2-(1-Methyl-1H-benzo[d]imidazol-2-yl)ethyl)azetidine-3-carboxamide hydrochloride
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