4-Pyrimidinamine,5-(ethoxymethyl)-2-methyl-
Suppliers
Names
[ CAS No. ]:
73-66-5
[ Name ]:
4-Pyrimidinamine,5-(ethoxymethyl)-2-methyl-
[Synonym ]:
EINECS 200-802-2
5-Aethoxymethyl-2-methyl-pyrimidin-4-ylamin
5-Ethoxymethyl-2-methylpyrimidin-4-ylamine
4-amino-5-ethoxymethyl-2-methylpyrimidine
4-Amino-2-methyl-5-ethoxymethylpyrimidine
2-Methyl-4-amino-5-<aethoxymethyl>-pyrimidin
2-methyl-4-amino-5-ethoxymethylpyrimidine
Chemical & Physical Properties
[ Density]:
1.113g/cm3
[ Boiling Point ]:
276.4ºC at 760 mmHg
[ Molecular Formula ]:
C8H13N3O
[ Molecular Weight ]:
167.20800
[ Flash Point ]:
121ºC
[ Exact Mass ]:
167.10600
[ PSA ]:
61.03000
[ LogP ]:
1.48490
[ Index of Refraction ]:
1.544
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UV6450000
- CHEMICAL NAME :
- Pyrimidine, 4-amino-5-(ethoxymethyl)-2-methyl-
- CAS REGISTRY NUMBER :
- 73-66-5
- BEILSTEIN REFERENCE NO. :
- 0139361
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C8-H13-N3-O
- MOLECULAR WEIGHT :
- 167.24
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1450 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,81,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 239 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,81,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 11 mg/m3/17W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
- REFERENCE :
- TNICS* Toxicology of New Industrial Chemical Substances. English translation of TPKVAL. (USSR Academy of Medical Sciences, Meditsina, Moscow, USSR) Volume(issue)/page/year: 13,59,1973 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- DOSE :
- 11 mg/m3
- SEX/DURATION :
- male 17 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
- REFERENCE :
- TNICS* Toxicology of New Industrial Chemical Substances. English translation of TPKVAL. (USSR Academy of Medical Sciences, Meditsina, Moscow, USSR) Volume(issue)/page/year: 13,59,1973 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1 mg/m3 JAN 1993
Safety Information
[ HS Code ]:
2933599090
Synthetic Route
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%