Propetamide

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Names

[ CAS No. ]:
730-07-4

[ Name ]:
Propetamide

[Synonym ]:
2-(4-ethoxyanilino)-N-propyl-propionamide
2-(4-ethoxyanilino)-N-propylpropanamide
(+-)-2-p-Phenetidino-propionsaeure-propylamid

Chemical & Physical Properties

[ Density]:
1.05g/cm3

[ Boiling Point ]:
457.9ºC at 760 mmHg

[ Molecular Formula ]:
C14H22N2O2

[ Molecular Weight ]:
250.33700

[ Flash Point ]:
230.7ºC

[ Exact Mass ]:
250.16800

[ PSA ]:
50.36000

[ LogP ]:
2.87580

[ Index of Refraction ]:
1.532

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TX1452471
CHEMICAL NAME :
Propanamide, 2-((4-ethoxyphenyl)amino)-N-propyl-
CAS REGISTRY NUMBER :
730-07-4
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C14-H22-N2-O2
MOLECULAR WEIGHT :
250.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 164,331,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1350 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 164,331,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2100 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 164,331,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1330 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 164,331,1966

Related Compounds

  • 2-[(4-Nitrophenyl)amino]-5-thiazolyl thiocyanate
  • 2-methyl-6-(1H-1,2,4-triazol-1-yl)hexan-2-amine
  • 4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanamido]-3-methoxybutanoic acid
  • 3-(4,4-Dimethylcyclohexyl)-4,4,4-trifluorobutanoic acid
  • Methyl 2-{spiro[4.5]decan-8-yl}acetate
  • 2-(1-Ethylpiperidin-4-yl)butanoic acid
  • 3-Amino-1-[2-(benzyloxy)ethyl]-1,4-dihydropyridin-4-one
  • 3-(1-aminoethyl)-1-(thian-4-yl)-1H-pyrazol-4-ol
  • 3-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoyl]-1,3-thiazolidine-4-carboxylic acid
  • 2-(1-Aminopropan-2-yl)pyridine-4-carboxylic acid
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