5-ethyl-1,3-dimethyl-5-phenyl-1,3-diazinane-2,4,6-trione

Names

[ CAS No. ]:
730-66-5

[ Name ]:
5-ethyl-1,3-dimethyl-5-phenyl-1,3-diazinane-2,4,6-trione

[Synonym ]:
BARBITURIC ACID,1,3-DIMETHYL-5-ETHYL-5-PHENYL
1,3-Dimethyl-5-ethyl-5-phenylbarbituric acid
Dimethylphenobarbital
1,3-dimethyl-5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione
5-ethyl-1,3-dimethyl-5-phenyl-pyrimidine-2,4,6-trione
1,3-Dimethylphenobarbitone
N,N-dimethylphenobarbital
5-ethyl-1,3-dimethyl-5-phenyl-barbituric acid
1,3-Dimethylphenobarbital

Chemical & Physical Properties

[ Molecular Formula ]:
C14H16N2O3

[ Molecular Weight ]:
260.28800

[ Exact Mass ]:
260.11600

[ PSA ]:
57.69000

[ LogP ]:
1.26060

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CQ4079000
CHEMICAL NAME :
Barbituric acid, 1,3-dimethyl-5-ethyl-5-phenyl-
CAS REGISTRY NUMBER :
730-66-5
BEILSTEIN REFERENCE NO. :
0268343
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H16-N2-O3
MOLECULAR WEIGHT :
260.32
WISWESSER LINE NOTATION :
T6VNVNV FHJ B1 D1 F2 FR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>250 mg/kg
TOXIC EFFECTS :
Behavioral - anticonvulsant Behavioral - sleep
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 16,1378,1973

Synthetic Route

Precursor & DownStream

Precursor

  • Methyl bromide
  • phenobarbital
  • 5-ethyl-1-methyl-5-phenyl-2-thioxo-1,2-dihydropyrimidine-4,6(3H,5H)-dione
  • diazomethane
  • mephobarbital
  • methyl iodide
  • Diethyl ether

DownStream


Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 2-[(2-Ethyl-4-thiazolyl)methoxy]-N-methylethanamine
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide