EPIROPRIM
Suppliers
Names
[ CAS No. ]:
73090-70-7
[ Name ]:
EPIROPRIM
[Synonym ]:
Ro 11-8958
2,4-Pyrimidinediamine,5-((3,5-diethoxy-4-(1H-pyrrol-1-yl)phenyl)methyl)
Epiroprima [INN-Spanish]
5-((3,5-Diethoxy-4-(1H-pyrrol-1-yl)phenyl)methyl)-2,4-pyrimidinediamine
Epiroprimum [INN-Latin]
Epiroprime [INN-French]
Epiroprim
Chemical & Physical Properties
[ Density]:
1.27g/cm3
[ Boiling Point ]:
626.5ºC at 760 mmHg
[ Molecular Formula ]:
C19H23N5O2
[ Molecular Weight ]:
353.41800
[ Flash Point ]:
332.7ºC
[ Exact Mass ]:
353.18500
[ PSA ]:
101.21000
[ LogP ]:
3.98230
[ Index of Refraction ]:
1.629
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UV8140650
- CHEMICAL NAME :
- 2,4-Pyrimidinediamine, 5-((3,5-diethoxy-4-(1H-pyrrol-1-yl)phenyl)methyl)-
- CAS REGISTRY NUMBER :
- 73090-70-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C19-H23-N5-O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1419 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- REFERENCE :
- JCHEEU Journal of Chemotherapy. (Edizioni Riviste Scientifiche, via R. Giuliani, 419, 50141 Florence, Italy) V.1- 1989- Volume(issue)/page/year: 5,400,1993
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JCHEEU Journal of Chemotherapy. (Edizioni Riviste Scientifiche, via R. Giuliani, 419, 50141 Florence, Italy) V.1- 1989- Volume(issue)/page/year: 5,400,1993