Iopidine
Suppliers
Names
[ CAS No. ]:
73218-79-8
[ Name ]:
Iopidine
[Synonym ]:
UNII-D2VW67N38H
Iopidine ophthalmic solution
MFCD00135922
2-(4-Amino-2,6-dichlorophenylimino)imidazolidine
2-[(4-amino-2,6-dichlorophenyl)imino]imidazolidine monohydrochloride
APRACLONIDINE HYDROCHLORIDE
ALO-2145
2,6-dichloro-1-N-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine,hydrochloride
p-aminoclonidine hydrochloride
NC 14 hydrochloride
2-[(2,6-dichloro-4-aminophenyl)imino]imidazolidine hydrochloride
p-aminoclonidine
mono hydrochloride
Apraclonidine HCl
Chemical & Physical Properties
[ Density]:
1.63 g/cm3
[ Boiling Point ]:
395.5ºC at 760 mmHg
[ Melting Point ]:
>230ºC
[ Molecular Formula ]:
C9H11Cl3N4
[ Molecular Weight ]:
281.56900
[ Flash Point ]:
193ºC
[ Exact Mass ]:
280.00500
[ PSA ]:
62.44000
[ LogP ]:
3.16730
[ Storage condition ]:
2-8°C
[ Stability ]:
Moisture Sensitive
[ Water Solubility ]:
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.4 mg/mL Solutions may be stored for several days at 4?#x00b0;C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CZ1582000
- CHEMICAL NAME :
- 1,4-Benzenediamine, 2,6-dichloro-N(sup 1)-(4,5-dihydro-1H-imidazol-2-yl)-, monohydrochloride
- CAS REGISTRY NUMBER :
- 73218-79-8
- LAST UPDATED :
- 199604
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C9-H10-Cl2-N4.Cl-H
- MOLECULAR WEIGHT :
- 281.59
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 38 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 24,557,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 24,557,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 24,557,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 24,557,1988
Safety Information
[ Symbol ]:
GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300-H370
[ Precautionary Statements ]:
Missing Phrase - N15.00950417-P308 + P311
[ Target Organs ]:
Cardio-vascular system
[ Hazard Codes ]:
T: Toxic;
[ Risk Phrases ]:
R23/24/25
[ Safety Phrases ]:
22-36/37/39-45
[ RIDADR ]:
UN 2811
[ WGK Germany ]:
3
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
2933290090
Customs
[ HS Code ]: 2933290090
[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%