1-Deoxynojirimycin hydrochloride

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Names

[ CAS No. ]:
73285-50-4

[ Name ]:
1-Deoxynojirimycin hydrochloride

[Synonym ]:
3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2R,3R,4R,5S)-, hydrochloride (1:1)
(+)-(2R,3R,4R,5S)-2-hydroxymethyl-3,4,5-trihydroxypiperidine hydrochloride
(+)-1-deoxynojirimycin hydrochloride
(2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol hydrochloride (1:1)
(+-)-1-Chlor-8,9-dihydro-inden
1H-Indene,1-chloro-3a,7a-dihydro
(1R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidinium chloride
(2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol hydrochloride (1:1)
Duvoglustat hydrochloride
1,5-dideoxy-1,5-imino-D-glucitol hydrochloride

Chemical & Physical Properties

[ Density]:
1.456 g/cm3

[ Boiling Point ]:
361.1ºC at 760 mmHg

[ Melting Point ]:
195-196ºC

[ Molecular Formula ]:
C6H14ClNO4

[ Molecular Weight ]:
199.633

[ Flash Point ]:
197.3ºC

[ Exact Mass ]:
199.061142

[ PSA ]:
92.95000

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

  • 5-azido-5-deoxy-1,2-O-benzylidene-α-D-glucofuranose
  • 5-benzyloxycarbonylamino-5-deoxy-1,2-O-isopropylidene-α-D-gluco-1,4-furanose
  • 2,3-di-O-benzyl-N-benzyloxycarbonyl-1,5-dideoxy-1,5-imino-D-glucitol
  • Deoxynojirimycin Tetrabenzyl Ether
  • 1-Deoxynojirimycin
  • (3R,4S)-3-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-7,7-dimethyl-4-prop-2-enoxy-2,6,8-trioxabicyclo[3.3.0]octane

DownStream

Articles

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

Production of the α-glycosidase inhibitor 1-deoxynojirimycin from Bacillus species.

Food Chem. 138(1) , 516-23, (2013)

1-Deoxynojirimycin (DNJ), a potent α-glycosidase inhibitor, has therapeutic applications in treatments of HIV, Gaucher's disease, and diabetes. DNJ has been extracted from natural sources (mulberry le...

Specificity of Processing α-glucosidase I is guided by the substrate conformation: crystallographic and in silico studies.

J. Biol. Chem. 288(19) , 13563-74, (2013)

The enzyme “GluI” is key to the synthesis of critical glycoproteins in the cell.We have determined the structure of GluI, and modeled binding with its unique sugar substrate.The specificity of this in...


More Articles

Related Compounds

  • (+)-1-Deoxynojirimycin hydrochloride
  • (+)-1-deoxynojirimycin hydrochloride
  • (3R,4R)-1-ethyl-2-(hydroxymethyl)piperidine-3,4,5-triol,hydrochloride
  • N-Cyclohexylpropyl Deoxynojirimycin, Hydrochloride
  • N-5-Carboxypentyl-1-deoxynojirimycin
  • (+)-3R-N-Monomethylamino-4c-phenyl-4t-ethoxycarbonylcyclohexene-1, hydrochloride
  • Methyl 2-amino-3-ethoxybenzoate
  • Ethyl 2-amino-3-ethoxybenzoate
  • 3-Methyl-2-phenylbut-2-en-1-amine
  • 3-(2-{[(tert-butoxy)carbonyl]amino}-1H-imidazol-4-yl)propanoic acid
  • 1-(4-Fluorobenzyl)-5-methyl-1h-pyrazol-4-amine
  • 4-Chloro-2-ethoxybenzaldehyde
  • 1-Cyclopropyl-3-ethyl-2,4-imidazolidinedione
  • Ethyl 2-amino-3,5-difluorobenzoate
  • 4-Chloro-2-(difluoromethoxy)phenol
  • 2-methyl-N-(1-phenylethyl)cyclopentan-1-amine
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