iopromide

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Names

[ CAS No. ]:
73334-07-3

[ Name ]:
iopromide

[Synonym ]:
iopromide
N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(méthoxyacétyl)amino]-N-méthylbenzène-1,3-dicarboxamide
N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methylisophthalamide
Ultravist
1,3-Benzenedicarboxamide, N,N-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-N-methyl-
iopromida
5-Methoxyacetylamino-2,4,6-triiodoisophthalic Acid [(2,3-Dihydroxy-N-methylpropyl)-(2,3-dihydroxypropyl)]diamide
N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiod-5-[(methoxyacetyl)amino]-N-methylbenzol-1,3-dicarboxamid
iopromidum
N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-N-methyl-5-{[(methyloxy)acetyl]amino}benzene-1,3-dicarboxamide
1,3-benzenedicarboxamide, N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methyl-
EINECS 277-385-9
Ultravist 300
N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methyl-1,3-benzenedicarboxamide
N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methylbenzene-1,3-dicarboxamide
Ultravist 370
UNII:712BAC33MZ
SHL 414C
1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-3-N-methylbenzene-1,3-dicarboxamide
MFCD00867924

Chemical & Physical Properties

[ Density]:
2.2±0.1 g/cm3

[ Boiling Point ]:
840.9±65.0 °C at 760 mmHg

[ Melting Point ]:
broad (160ºC transition)

[ Molecular Formula ]:
C18H24I3N3O8

[ Molecular Weight ]:
791.112

[ Flash Point ]:
462.4±34.3 °C

[ Exact Mass ]:
790.869690

[ PSA ]:
168.66000

[ LogP ]:
-2.95

[ Vapour Pressure ]:
0.0±3.3 mmHg at 25°C

[ Index of Refraction ]:
1.710

[ Storage condition ]:
Hygroscopic, -20?C Freezer, Under Inert Atmosphere

[ Stability ]:
Hygroscopic

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CZ2230000
CHEMICAL NAME :
1,3-Benzenedicarboxamide, N,N'-bis(2,3-dihydroxypropyl)-5-((methoxyacetyl)amino )-N-methyl- 2,4,6-triiodo-
CAS REGISTRY NUMBER :
73334-07-3
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C18-H24-I3-N3-O8
MOLECULAR WEIGHT :
791.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
21403 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 370,41,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
34 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AAJNDL AJNR, American Journal of Neuroradiology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1980- Volume(issue)/page/year: 4,350,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>21 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 44,1275,1994

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H410

[ Precautionary Statements ]:
P273-P501

[ Hazard Codes ]:
N

[ Risk Phrases ]:
50/53

[ Safety Phrases ]:
60-61

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
CZ2230000

[ HS Code ]:
2924299090

Synthetic Route

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Related Compounds

  • Iopromide
  • Desmethoxy Iopromide
  • Iopromide Impurity 44
  • Iopromide EP Impurity D
  • Iopromide EP Impurity F
  • Iopromide EP Impurity C
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  • 4-Fluoroazocan-5-ol
  • 8-Chloro-7-methylquinoline-3,4-diamine
  • 6-Bromo-4-chloro-5-fluoro-3-nitroquinoline
  • 4,5-Dichloro-8-iodo-3-nitroquinoline
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  • 6-Cyclopropylquinoline-3,4-diamine
  • Furo[3,2-b]pyridin-3(2H)-one, 6-(trifluoromethyl)-
  • 5-Cyclopropyl-2-fluoropyridine-3-carboxylic acid
  • 8-chloro-6-fluoro-N4,5-dimethylquinoline-3,4-diamine
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