Geldanamycin,18,21-didehydro-6,17-didemethoxy-18,21-dideoxo-18,21-dihydroxy-15-methoxy-6-methyl-11-O-methyl-,(6S,15R)-

Suppliers

Names

[ CAS No. ]:
73341-73-8

[ Name ]:
Geldanamycin,18,21-didehydro-6,17-didemethoxy-18,21-dideoxo-18,21-dihydroxy-15-methoxy-6-methyl-11-O-methyl-,(6S,15R)-

[Synonym ]:
macbecin II

Chemical & Physical Properties

[ Density]:
1.19g/cm3

[ Boiling Point ]:
698.9ºC at 760 mmHg

[ Molecular Formula ]:
C30H44N2O8

[ Molecular Weight ]:
560.67900

[ Flash Point ]:
376.5ºC

[ Exact Mass ]:
560.31000

[ PSA ]:
149.57000

[ LogP ]:
5.81680

[ Index of Refraction ]:
1.565

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OL9056000
CHEMICAL NAME :
Macbecin II
CAS REGISTRY NUMBER :
73341-73-8
LAST UPDATED :
198509
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C30-H44-N2-O8.H2-O
MOLECULAR WEIGHT :
578.78
WISWESSER LINE NOTATION :
T6-19- A GMV IU KU OU&TJ AQ DQ I1 M1 NOVZ O1 Q1 RO1 SO1 U1 VO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Rodent - mouse Leukocyte
DOSE/DURATION :
10 umol/L
REFERENCE :
PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 24,321,1983

Precursor & DownStream

Precursor

DownStream

  • Ethanoic anhydride

Related Compounds

  • Tert-butyl ({4-bromo-5-[(3-methoxyphenyl)sulfonyl]-2-thienyl}methyl)methylcarbamate
  • 3-Piperidinecarboxylic acid, 4-phenyl-, cis-
  • 5-(4-Bromophenyl)morpholin-3-one
  • Tert-butyl {[4-bromo-5-(phenylthio)-2-thienyl]methyl}methylcarbamate
  • 2-(2-Bromo-5-fluorophenyl)-2-methylpropanoic acid
  • 1,6,7,11balpha-Tetrahydro-1alpha,7alpha-bis(4-hydroxyphenyl)benzo[6,7]cyclohepta[1,2,3-cd]benzofuran-4,6beta,8,10-tetrol
  • 5-[3-(benzyloxy)-4-methoxyphenyl]-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one
  • 3H-1,2,4-Triazole-3-thione, 2,4-dihydro-4-[1-methyl-2-(2-thienyl)ethyl]-
  • 2-[(Methylsulfamoyl)amino]acetic acid
  • ({1-[(oxolan-3-yl)methyl]-1H-1,2,3-triazol-4-yl}methyl)(propyl)amine
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.