N-(4-methyl-1,3-thiazol-2-yl)acetamide

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Names

[ CAS No. ]:
7336-51-8

[ Name ]:
N-(4-methyl-1,3-thiazol-2-yl)acetamide

[Synonym ]:
N-(4-methyl-1,3-thiazol-2-yl)acetamide
MFCD00011561

Chemical & Physical Properties

[ Density]:
1.285g/cm3

[ Melting Point ]:
134-136ºC(lit.)

[ Molecular Formula ]:
C6H8N2OS

[ Molecular Weight ]:
156.20600

[ Exact Mass ]:
156.03600

[ PSA ]:
70.23000

[ LogP ]:
1.48290

[ Index of Refraction ]:
1.604

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Methylthiazol-2-amine
  • Ethanoic anhydride
  • Acetyl chloride
  • Chlorotributyltin
  • N-(5-BROMO-4-METHYLTHIAZOL-2-YL)ACETAMIDE
  • N-(acetyl-thiocarbamoyl)-alanine
  • 2-Acetylamino-4-methylthiazole-5-carboxylic acid
  • Chloroacetone

DownStream

  • N-(5-IODO-4-METHYLTHIAZOL-2-YL)ACETAMIDE
  • N-(5-BROMO-4-METHYLTHIAZOL-2-YL)ACETAMIDE
  • N-(4-methyl-5-nitro-1,3-thiazol-2-yl)acetamide
  • 2-Acetamido-4-methyl-5-thiazolesulfonyl chloride

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

The metabolism of acetamidothiazoles in the rat. 2-Acetamido-, 2-acetamido-4-methyl- and 2-acetamido-4-phenyl-thiazole.

Biochem. J. 134(4) , 869-78, (1973)

The metabolism of some anti-inflammatory acetamidothiazoles was studied in the rat. The main metabolites were the corresponding acetylthiohydantoic acids, produced by fission of the thiazole ring. Min...

Notes-2-Aminothiazolesulfonamides. Ziegler C, et al.

J. Org. Chem. 25(8) , 1454-55, (1960)


More Articles

Related Compounds

  • 2-cyano-N-(4-methyl-1,3-thiazol-2-yl)acetamide
  • 2-chloro-N-(4-methyl-1,3-thiazol-2-yl)acetamide
  • 2-hydroxy-N-(4-methyl-1,3-thiazol-2-yl)acetamide
  • 2,2,2-trifluoro-N-(4-methyl-1,3-thiazol-2-yl)acetamide
  • 2-[4-(1,3-Benzothiazol-2-yl)-1-piperidinyl]-N-(4-methyl-1,3-thiazol-2-yl)acetamide
  • 2-[(5-Benzyl-4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)acetamide