Fenflumizole

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Names

[ CAS No. ]:
73445-46-2

[ Name ]:
Fenflumizole

[Synonym ]:
Fenflumizolum [INN-Latin]
4,5-Bis(4-methoxyphenyl)-2-(2,4-difluorophenyl)-1H-imidazole
2-(2,4-difluorophenyl)-4,5-bis(4-methoxyphenyl)imidazole
1H-Imidazole,4,5-bis(4-methoxyphenyl)-2-(2,4-difluorophenyl)
Fenflumizole
Fenflumizole [INN]
Fenflumizolum
2-(2,4-Difluorphenyl)-4,5-bis(4-methoxyphenyl)imidazole
Fenflumizole [INN-French]

Chemical & Physical Properties

[ Density]:
1.252g/cm3

[ Boiling Point ]:
555.2ºC at 760 mmHg

[ Molecular Formula ]:
C23H18F2N2O2

[ Molecular Weight ]:
392.39800

[ Flash Point ]:
289.6ºC

[ Exact Mass ]:
392.13400

[ PSA ]:
47.14000

[ LogP ]:
5.70610

[ Index of Refraction ]:
1.591

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NI3517140
CHEMICAL NAME :
1H-Imidazole, 4,5-bis(4-methoxyphenyl)-2-(2,4-difluorophenyl)-
CAS REGISTRY NUMBER :
73445-46-2
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C23-H18-F2-N2-O2
MOLECULAR WEIGHT :
392.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 53,288,1983

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • diphenylisobenzofuran

DownStream

Related Compounds

  • 4-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methoxy-N-methylpropanamido]benzoic acid
  • 2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methoxy-N-methylpropanamido]benzoic acid
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-({[1-(1H-pyrazol-1-yl)cyclopropyl]methyl}carbamoyl)propanoic acid
  • 3-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-imidazol-5-yl)propanamido]-2-methylbutanoic acid
  • 1-[1-(2-Bromo-3-hydroxy-4-methoxyphenyl)cyclopropyl]ethan-1-one
  • (2S)-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-imidazol-5-yl)-N-methylpropanamido]propanoic acid
  • 2-[(2S)-N-cyclopropyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-imidazol-5-yl)propanamido]acetic acid
  • 4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-{[1-(propylsulfanyl)propan-2-yl]carbamoyl}butanoic acid
  • 1-(2-chloro-4-methylphenyl)-N-ethyl-1H-pyrazole-5-sulfonamide
  • 1-(3,5-dimethylphenyl)-N-ethyl-1H-pyrazole-5-sulfonamide
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