Fenflumizole

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Names

[ CAS No. ]:
73445-46-2

[ Name ]:
Fenflumizole

[Synonym ]:
Fenflumizolum [INN-Latin]
4,5-Bis(4-methoxyphenyl)-2-(2,4-difluorophenyl)-1H-imidazole
2-(2,4-difluorophenyl)-4,5-bis(4-methoxyphenyl)imidazole
1H-Imidazole,4,5-bis(4-methoxyphenyl)-2-(2,4-difluorophenyl)
Fenflumizole
Fenflumizole [INN]
Fenflumizolum
2-(2,4-Difluorphenyl)-4,5-bis(4-methoxyphenyl)imidazole
Fenflumizole [INN-French]

Chemical & Physical Properties

[ Density]:
1.252g/cm3

[ Boiling Point ]:
555.2ºC at 760 mmHg

[ Molecular Formula ]:
C23H18F2N2O2

[ Molecular Weight ]:
392.39800

[ Flash Point ]:
289.6ºC

[ Exact Mass ]:
392.13400

[ PSA ]:
47.14000

[ LogP ]:
5.70610

[ Index of Refraction ]:
1.591

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NI3517140
CHEMICAL NAME :
1H-Imidazole, 4,5-bis(4-methoxyphenyl)-2-(2,4-difluorophenyl)-
CAS REGISTRY NUMBER :
73445-46-2
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C23-H18-F2-N2-O2
MOLECULAR WEIGHT :
392.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 53,288,1983

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • diphenylisobenzofuran

DownStream

Related Compounds

  • 3-(3-chlorophenyl)-7-(3,4-difluorophenyl)-2-methylpyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6(7H)-one
  • 5-(3-Chlorophenyl)-11-(3,4-difluorophenyl)-4-methyl-2,3,7,8,11-pentazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,12-pentaen-10-one
  • 3-(3-chlorophenyl)-2-methyl-7-(1,3-thiazol-2-yl)pyrazolo[5,1-c]pyrido[4,3-e][1,2,4]triazin-6(7H)-one
  • N-{4-[2-ethyl-3-(4-methoxyphenyl)-6-oxopyrazolo[5,1-c]pyrido[4,3-e][1,2,4]triazin-7(6H)-yl]phenyl}acetamide
  • 2-ethyl-3-(4-methoxyphenyl)-7-[2-(trifluoromethyl)phenyl]pyrazolo[5,1-c]pyrido[4,3-e][1,2,4]triazin-6(7H)-one
  • 7-(3,4-dichlorophenyl)-2-ethyl-3-(4-methoxyphenyl)pyrazolo[5,1-c]pyrido[4,3-e][1,2,4]triazin-6(7H)-one
  • 7-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethyl-3-(4-methoxyphenyl)pyrazolo[5,1-c]pyrido[4,3-e][1,2,4]triazin-6(7H)-one
  • 7-(2,3-dichlorophenyl)-2-ethyl-3-(4-methoxyphenyl)pyrazolo[5,1-c]pyrido[4,3-e][1,2,4]triazin-6(7H)-one
  • 3-(4-bromophenyl)-7-(4-methoxyphenyl)-2-methylpyrazolo[5,1-c]pyrido[4,3-e][1,2,4]triazin-6(7H)-one
  • N-(Piperidin-1-YL)pyrimidin-2-amine
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