N-tert-Butyl-α-(2-sulfophenyl)nitrone sodium salt

Names

[ Name ]:
N-tert-Butyl-α-(2-sulfophenyl)nitrone sodium salt

[Synonym ]:
N-tret-butyl-α-phenylnitrone
sodium tert-butyl(1-sulfonatobenzylidene)amine-N-oxide
MFCD00012017
sodium 2-[(tert-butylimino)methyl]benzenesulfonate N-oxide

Chemical & Physical Properties

[ Melting Point ]:
246 °C (dec.) (lit.)

[ Molecular Formula ]:
C₁₁H₁₄NNaO₄S

[ Molecular Weight ]:
279.28800

[ Exact Mass ]:
279.05400

[ PSA ]:
94.33000

[ LogP ]:
2.92240

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
NONH for all modes of transport

Articles

Atypical effect of some spin trapping agents: reversible inhibition of acetylcholinesterase.

Free Radic. Biol. Med. 28(4) , 597-603, (2000)

N-tert-butyl-alpha-phenylnitrone (PBN), a widely used nitrone-based free radical trap was recently shown to prevent acetylcholinesterase (AChE) inhibitors induced muscle fasciculations and brain seizu...

Effects of cytisine on hydroxyl radicals in vitro and MPTP-induced dopamine depletion in vivo.

Eur. J. Pharmacol. 360(2-3) , 155-63, (1998)

The potential new iron-chelator cytisine and the radical scavenger N-tert-butyl-alpha-(2-sulfophenyl) nitrone (S-PBN) were incubated in a Fenton system and hydroxyl radical formation was measured with...

Comparison of the radical trapping ability of PBN, S-PPBN and NXY-059.

Free Radic. Res. 34(4) , 417-26, (2001)

The nitrones alpha-phenyl-N-tert-butyl nitrone (PBN), sodium 2-sulfophenyl-N-tert-butyl nitrone (S-PBN) and disodium 2,4-disulfophenyl-N-tert-butyl nitrone (NXY-059) are neuroprotective in a variety o...