Quinpirole dihydrochloride

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Names

[ CAS No. ]:
73625-62-4

[ Name ]:
Quinpirole dihydrochloride

[Synonym ]:
(+/-)-quinpirole dihydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C13H22ClN3

[ Molecular Weight ]:
255.78700

[ Exact Mass ]:
255.15000

[ PSA ]:
31.92000

[ LogP ]:
2.73880

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Dopamine D2 receptor activity modulates Akt signaling and alters GABAergic neuron development and motor behavior in zebrafish larvae.

J. Neurosci. 31 , 5512-25, (2011)

An imbalance in dopamine-mediated neurotransmission is a hallmark physiological feature of neuropsychiatric disorders, such as schizophrenia. Recent evidence demonstrates that dopamine D(2) receptors,...

A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease.

Hum. Mol. Genet. 24(7) , 1929-44, (2015)

The essential micronutrient manganese is enriched in brain, especially in the basal ganglia. We sought to identify neuronal signaling pathways responsive to neurologically relevant manganese levels, a...

Biphasic effect of D-2 agonist quinpirole on locomotion and movements.

Eur. J. Pharmacol. 161 , 151-157, (1989)

The effects of the D-2 agonist quinpirole on forward progression, and on vertical and lateral movements, were measured for 2 h in rats injected with either saline, 0.03, 0.125, 0.5 or 8 mg/kg of the d...


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