Pyridoxal isonicotinoyl hydrazone
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Names
[ CAS No. ]:
737-86-0
[ Name ]:
Pyridoxal isonicotinoyl hydrazone
[Synonym ]:
pyridoxal N-(isonicotinoyl)hydrazone
Pyridoxal hydrochloride 1GR
pyridoxal HCl
PL HCL
PyridoxalHydrochlorideMin.
Pyridoxal,Hydrochlorid
3-hydroxy-5-hydroxymethyl-2-methyl-pyridine-4-carbaldehyde,hydrochloride
Pyridoxal-[2H3] hydrochloride
Pyridoxal hydrochloride 5GR
Pyridoxal hydrochlor
3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde,hydrochloride
pyridoxal isonicotinoyl hydrazone
Pyridoxalhydrochloride
Chemical & Physical Properties
[ Density]:
1.35g/cm3
[ Molecular Formula ]:
C14H14N4O3
[ Molecular Weight ]:
286.29
[ Exact Mass ]:
286.10700
[ PSA ]:
107.70000
[ LogP ]:
1.13770
[ Index of Refraction ]:
1.646
[ Storage condition ]:
2-8℃
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- US5760000
- CHEMICAL NAME :
- 4-Pyridinecarboxylic acid, ((3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl)me thylene) hydrazide
- CAS REGISTRY NUMBER :
- 737-86-0
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C14-H14-N4-O3
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Kidney, Ureter, Bladder - other changes in urine composition
- REFERENCE :
- DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 14,395,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Liver - fatty liver degeneration
- REFERENCE :
- DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 14,395,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4500 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Kidney, Ureter, Bladder - other changes in urine composition
- REFERENCE :
- DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 14,395,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Liver - fatty liver degeneration
- REFERENCE :
- DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 14,395,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 72 gm/kg/90D-C
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Related to Chronic Data - death
- REFERENCE :
- DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 14,395,1991