ethyl 4-(1H-benzimidazol-2-ylamino)piperidine-1-carboxylate

Names

[ CAS No. ]:
73734-07-3

[ Name ]:
ethyl 4-(1H-benzimidazol-2-ylamino)piperidine-1-carboxylate

[Synonym ]:
EINECS 277-580-9
ethyl 4-(1H-benzo[d]imidazol-2-ylamino)piperidin-1-carboxylate
ethyl 4-[(3H-imidazo[4,5-b]pyridin-2-yl)amino]-1-piperdinecarboxylate
ethyl 4-(1H-benzimidazol-2-ylamino)-1-piperidine-carboxylate
4-(1H-Benzimidazol-2-ylamino)-1-(ethoxycarbonyl)piperidine
(1H-benzimidazol-2-yl)-(1-ethoxycarbonyl-piperidin-4-yl)amine

Chemical & Physical Properties

[ Density]:
1.297g/cm3

[ Boiling Point ]:
482.1ºC at 760 mmHg

[ Molecular Formula ]:
C15H20N4O2

[ Molecular Weight ]:
288.34500

[ Flash Point ]:
245.4ºC

[ Exact Mass ]:
288.15900

[ PSA ]:
73.48000

[ LogP ]:
1.95550

[ Index of Refraction ]:
1.657

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl 4-{[(2-aminophenyl)aminothioxomethyl]amino}-1-piperidinecarboxylate
  • 2-Chlorobenzimidazole
  • N-Carbethoxy-4-amino-piperidone
  • methyl iodide
  • ethyl 4-isothiocyanatopiperidine-1-carboxylate
  • sodium carbonate

DownStream

  • 4-[[1-[(4-FLUOROPHENYL)-METHYL]-1H-BENZIMIDAZOLE-2-YL]AMINO]-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER
  • Astemizole
  • O-Desmethyl Astemizole
  • 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(2-pyridinyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine
  • (1-ETHYLPROPYL)BENZENE
  • Norastemizole Hydrobromide
  • norastemizole

Related Compounds

  • 2-{5-amino-4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-3-(methylsulfanyl)-1H-pyrazol-1-yl}-N-(4-chlorophenyl)acetamide
  • 2-{5-amino-4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-3-(methylsulfanyl)-1H-pyrazol-1-yl}-N-(2-chloro-4-fluorophenyl)acetamide
  • 2-{5-amino-4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-3-(methylsulfanyl)-1H-pyrazol-1-yl}-N-(3-chlorophenyl)acetamide
  • 2-{5-amino-4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-3-(methylsulfanyl)-1H-pyrazol-1-yl}-N-(3-fluorophenyl)acetamide
  • 2-{5-amino-4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-3-(methylsulfanyl)-1H-pyrazol-1-yl}-N-(3-methoxyphenyl)acetamide
  • 2-{5-amino-4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-3-(methylsulfanyl)-1H-pyrazol-1-yl}-N-[3-(methylsulfanyl)phenyl]acetamide
  • 2-{5-amino-4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-3-(methylsulfanyl)-1H-pyrazol-1-yl}-N-(2-methoxyphenyl)acetamide
  • (Z)-N-(2-(4-methoxyphenyl)-5,5-dioxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-3-(3,4,5-trimethoxyphenyl)acrylamide
  • (Z)-3-(3,4-dimethoxyphenyl)-N-(2-(4-methoxyphenyl)-5,5-dioxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acrylamide
  • (2Z)-3-(1,3-benzodioxol-5-yl)-N-[2-(4-methoxyphenyl)-5,5-dioxido-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl]acrylamide
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