6-amino-2-(fluoromethyl)-3-[2-(hydroxymethyl)phenyl]quinazolin-4-one

Names

[ CAS No. ]:
73832-13-0

[ Name ]:
6-amino-2-(fluoromethyl)-3-[2-(hydroxymethyl)phenyl]quinazolin-4-one

[Synonym ]:
6-amino-2-fluoromethyl-3-(o-hydroxymethylphenyl)-4(3H)-quinazolinone
4(3H)-Quinazolinone,6-amino-2-(fluoromethyl)-3-(2-(hydroxymethyl)phenyl)
6-amino-2-fluoromethyl-3-(2-hydroxymethyl-phenyl)-3H-quinazolin-4-one
6-Amino-2-(fluoromethyl)-3-(2-(hydroxymethyl)phenyl)-4(3H)-quinazolinone
6-amino-2-(fluoromethyl)-3-[2-(hydroxymethyl)phenyl]quinazolin-4(3H)-one

Chemical & Physical Properties

[ Density]:
1.39g/cm3

[ Boiling Point ]:
562ºC at 760 mmHg

[ Molecular Formula ]:
C16H14FN3O2

[ Molecular Weight ]:
299.30000

[ Flash Point ]:
293.7ºC

[ Exact Mass ]:
299.10700

[ PSA ]:
81.14000

[ LogP ]:
2.51090

[ Index of Refraction ]:
1.659

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-fluoromethyl-3-(o-hydroxymethylphenyl)-6-nitro-4(3H)-quinazolinone
  • (2-Aminophenyl)methanol
  • 2-fluoroacetamido-5-nitrobenzoic acid

DownStream

Related Compounds

  • 4-(3,5-dimethyl-1H-pyrazol-1-yl)-2-methyl-6-{4-[4-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl}pyrimidine
  • 2-[5-(6-tert-butylpyridazin-3-yl)-octahydropyrrolo[3,4-c]pyrrol-2-yl]-4H-pyrido[1,2-a]pyrimidin-4-one
  • 7-Fluoro-3-({1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]piperidin-4-yl}methyl)-3,4-dihydroquinazolin-4-one
  • 2-Cyclopropyl-4-[4-(6-pyrazol-1-ylpyrimidin-4-yl)piperazin-1-yl]pyrimidine
  • 3-[4-(6-cyclopropylpyrimidin-4-yl)piperazin-1-yl]-6-(1H-pyrazol-1-yl)pyridazine
  • 4-[4-(6-cyclopropylpyrimidin-4-yl)piperazin-1-yl]-6-(1H-pyrazol-1-yl)pyrimidine
  • 2-cyclopropyl-4-{4-[6-(1H-pyrazol-1-yl)pyridazin-3-yl]piperazin-1-yl}pyrimidine
  • 7-Fluoro-3-[[1-[2-(4-methylpyrazol-1-yl)ethyl]piperidin-4-yl]methyl]quinazolin-4-one
  • 2-Cyclopropyl-5-[4-[6-(3-methylpyrazol-1-yl)pyridazin-3-yl]piperazin-1-yl]-1,3,4-thiadiazole
  • 2-cyclopropyl-4-{4-[6-(3-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]piperazin-1-yl}pyrimidine
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