4-(N-BOC-AMINO)PIPERIDINE

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Names

[ CAS No. ]:
73874-95-0

[ Name ]:
4-(N-BOC-AMINO)PIPERIDINE

[Synonym ]:
2-Methyl-2-propanyl 4-amino-1-piperidinecarboxylate
Carbamic acid, N-4-piperidinyl-, 1,1-dimethylethyl ester
MFCD00798171
methanol, 1-(1,1-dimethylethoxy)-1-(4-piperidinylimino)-, (E)-
tert-butyl N-piperidin-4-ylcarbamate
tert-butyl-piperidin-4-ylcarbamat
2-Methyl-2-propanyl 4-piperidinylcarbamate
tert-butyl piperidin-4-ylcarbamate
4-(N-BOC-AMINO)PIPERIDINE
4-(tert-Butoxycarbonyl)-aminopiperidine
4-N-BOC-Aminopiperidine
4-N-(tert-Butoxycarbonyl)aminopiperidine

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
304.8±31.0 °C at 760 mmHg

[ Melting Point ]:
162-166 °C(lit.)

[ Molecular Formula ]:
C10H20N2O2

[ Molecular Weight ]:
200.28

[ Flash Point ]:
138.2±24.8 °C

[ Exact Mass ]:
200.152481

[ PSA ]:
50.36000

[ LogP ]:
1.32

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.480

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Benzyl-4-(N-Boc-amino)piperidine
  • 4-Amino-1-benzylpiperidine
  • Di-tert-butyl dicarbonate
  • 1-BOC-4-CBZ-AMINO-PIPERIDINE
  • Benzyl 4-isocyanato-1-piperidinecarboxylate

DownStream

  • 1-isoquinolin-5-ylsulfonylpiperidin-4-amine
  • 4-Amino-1-(methylsulfonyl)piperidine
  • 4-(4-tert-butoxycarbonylamino-piperidine-1-carbonyl)-piperidine-1-carboxylic acid benzyl ester
  • (4-Boc-Amino-piperidin-1-yl)acetic acid ethylester
  • TERT-BUTYL (1-(METHYLSULFONYL)PIPERIDIN-4-YL)CARBAMATE
  • 2-(4-([(TERT-BUTOXY)CARBONYL]AMINO)PIPERIDIN-1-YL)ACETIC ACID
  • (5'-Methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-carbamic acid tert-butyl ester
  • 1-ACETYL-4-BOCAMINO-PIPERIDINE
  • 1-(4-METHOXYPHENETHYL)PIPERIDIN-4-AMINE
  • R547

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Discovery of a piperidine-4-carboxamide CCR5 antagonist (TAK-220) with highly potent Anti-HIV-1 activity.

J. Med. Chem. 49 , 2784, (2006)

We incorporated various polar groups into previously described piperidine-4-carboxamide CCR5 antagonists to improve their metabolic stability in human hepatic microsomes. Introducing a carbamoyl group...

Synthesis of potent oxindole CDK2 inhibitors.

Bioorg. Med. Chem. 11 , 1873-1881, (2003)

A series of oxindole CDK2 inhibitors was synthesized. These novel analogues have a saturated monosubstituted cyclic moiety at their C-4 position that mimics the ribofuranoside of ATP. This substitutio...

Poly (2-isopropyl-2-oxazoline)-poly (L-glutamate) block copolymers through ammonium-mediated NCA polymerization. Meyer M and Schlaad H.

Macromolecules 39(11) , 3967-3970, (2006)


More Articles

Related Compounds

  • 1-Benzyl-4-(N-Boc-amino)piperidine
  • METHYL 4-((TERT-BUTOXYCARBONYL)AMINO)PIPERIDINE-4-CARBOXYLATE
  • (1-Phenethyl-piperidin-4-yl)-carbamic acid tert-butyl ester
  • 4-n-boc-amino-4-carboxytetrahydrothiopyran
  • 4-N-Boc-amino-3-methoxyphenylboronic acid
  • 4-(N-Boc-amino)-3-oxo-pentanoic Acid Methyl Ester
  • tert-butyl N-[3-[2-(4-chloroimidazol-1-yl)-5-nitrophenoxy]propyl]carbamate
  • 2-[(1-Hydroxypropan-2-yl)sulfanyl]-1-(4-methylphenyl)ethan-1-one
  • 3-Benzyloxy-6-methoxy-[1,5]naphthyridine-4-carbonitrile
  • 1-[(1-Methyl-1h-1,2,3-triazol-4-yl)methyl]cyclopropane-1-carboxylic acid
  • 4-iodo-1-(4-methoxybenzyl)-1H-pyrazole-3-carboxylic acid
  • 2-[(1-Hydroxypropan-2-yl)sulfanyl]-1-(3-methylphenyl)ethan-1-one
  • 1-(4-Methoxybenzyl)-3-bromo-1H-pyrazole-4-carboxylic acid
  • 2-methyl-1-(1-methyl-1H-1,2,3-triazol-4-yl)propan-2-ol
  • 1-Bromo-2-methyl-4-(2,2,2-trifluoroethoxy)benzene
  • 3-[(1-methyl-1H-1,2,3-triazol-4-yl)methyl]piperidin-3-ol
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