2-Fluoro-6-methoxyphenol

Names

[ CAS No. ]:
73943-41-6

[ Name ]:
2-Fluoro-6-methoxyphenol

[Synonym ]:
MFCD00075140
2-fluoro-6-methoxyphenol

Chemical & Physical Properties

[ Density]:
1.23 g/mL at 25 °C(lit.)

[ Boiling Point ]:
130-131 °C36 mm Hg(lit.)

[ Molecular Formula ]:
C₇H₇FO₂

[ Molecular Weight ]:
142.12800

[ Flash Point ]:
218 °F

[ Exact Mass ]:
142.04300

[ PSA ]:
29.46000

[ LogP ]:
1.53990

[ Index of Refraction ]:
n20/D 1.52(lit.)

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2909500000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1-FLUORO-2,3-DIMETHOXYBENZENE
3-Fluoroanisole

DownStream

Benzeneacetonitrile,3-fluoro-4,5-dihydroxy-
1-FLUORO-2,3-DIMETHOXYBENZENE
3-Fluoro-4-hydroxy-5-methoxybenzaldehyde
2-fluoro-3-hydroxy-4-methoxybenzaldehyde
4-(DIMETHYLAMINOMETHYL)-6-FLUORO-2-METHOXYPHENOL
3-fluorocatechol
Benzene,1-(chloromethyl)-2-fluoro-3,4-dimethoxy-
[2-(2-fluoro-3,4-dimethoxy)phenyl]ethylamine
2-FLUORO-3,4-DIMETHOXYPHENYLACETONITRILE

Customs

[ HS Code ]: 2909500000

[ Summary ]:
2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Receptor activity and conformational analysis of 5'-halogenated resiniferatoxin analogs as TRPV1 ligands.

Bioorg. Med. Chem. Lett. 21(1) , 299-302, (2011)

A series of 5'-halogenated resiniferatoxin analogs have been investigated in order to examine the effect of halogenation in the A-region on their binding and the functional pattern of agonism/antagoni...

4-Bromo-2-fluoro-6-methoxyphenol
3-Bromo-2-fluoro-6-methoxyphenol
4-[(dimethylamino)methyl]-2-fluoro-6-methoxyphenol
2-fluoro-4-(iodomethyl)-6-methoxyphenol
2-Fluoro-4-(hydroxymethyl)-6-methoxyphenol
2-FLUORO-6-METHYLBENZYLBROMIDE
2-(1-methyl-1H-tetrazol-5-yl)morpholine hydrochloride
[5-Fluoro-2-(4-methylpiperazin-1-yl)phenyl]methanamine;dihydrochloride
Sodium;1-pyridin-4-ylcyclopentane-1-carboxylate
(3-Methyl-1-benzothiophen-5-yl)methanamine;hydrochloride
Methyl 2-ethynyl-6-fluorobenzoate
(1R)-1-(4,4-difluorocyclohexyl)-2,2-difluoroethan-1-amine
rac-(1R,2S)-1-methoxy-N-methyl-2,3-dihydro-1H-inden-2-amine hydrochloride
3-(Phenylmethoxymethyl)azetidine-3-carboxylic acid;hydrochloride
1-{1-Chlorospiro[2.3]hexan-1-yl}methanamine
8,8-Dimethyl-7,9-dioxa-2-azaspiro[4.5]decane

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