1-[(2R,4R,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione

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Names

[ CAS No. ]:
73971-82-1

[ Name ]:
1-[(2R,4R,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione

[Synonym ]:
5'OHCH2alloAZT
3'-azido-3'-deoxythymidine

Chemical & Physical Properties

[ Molecular Formula ]:
C10H13N5O4

[ Molecular Weight ]:
267.24

[ Exact Mass ]:
267.09700

[ PSA ]:
134.33000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-(3-beta-Azido-2,3-dideoxy-5-O-trityl-beta-D-threopenta-furanosyl)thyMine
  • 5-methyl-1-[4-methylsulfonyloxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
  • (+)-(2E,4S)-5-Acetoxy-4-(formyloxy)-2-pentenal
  • 4,5-O-cyclohexylidene-2,3-dideoxy-aldehydo-D-glycero-trans-pent-2-enose
  • 5-O-acetyl-3-azido-1-O-(4-biphenylcarbonyl)-2,3-dideoxy-D-threo-pentofuranose
  • 5'-O-Tritylthymidine

DownStream