N-(2-methoxyethyl)-5-nitro-pyridin-2-amine

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Names

[ CAS No. ]:
74037-56-2

[ Name ]:
N-(2-methoxyethyl)-5-nitro-pyridin-2-amine

[Synonym ]:
Pyridine,2-((2-methoxyethyl)amino)-5-nitro
2-((2-Methoxyethyl)amino)-5-nitropyridine
2-Pyridinamine,N-(2-methoxyethyl)-5-nitro

Chemical & Physical Properties

[ Density]:
1.286g/cm3

[ Boiling Point ]:
357.7ºC at 760 mmHg

[ Molecular Formula ]:
C8H11N3O3

[ Molecular Weight ]:
197.19100

[ Flash Point ]:
170.1ºC

[ Exact Mass ]:
197.08000

[ PSA ]:
79.97000

[ LogP ]:
1.64430

[ Index of Refraction ]:
1.586

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UT5100000
CHEMICAL NAME :
Pyridine, 2-((2-methoxyethyl)amino)-5-nitro-
CAS REGISTRY NUMBER :
74037-56-2
LAST UPDATED :
197901
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H11-N3-O3
MOLECULAR WEIGHT :
197.22
WISWESSER LINE NOTATION :
T6NJ BM2O1 ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03679

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Chloro-5-nitropyridine
  • 2-Methoxyethanamine
  • 5-nitropyridin-2-ol

DownStream

  • N2-(2-Methoxyethyl)-2,5-pyridinediamine

Related Compounds

  • N-(2-methoxyethyl)pyridin-2-amine
  • N-[(2-methoxy-5-tert-butyl-phenyl)methylideneamino]-5-nitro-pyridin-2-amine
  • N-(2,5-difluorophenyl)-3-nitropyridin-2-amine
  • N-(2,5-dimethoxyphenyl)-3-nitropyridin-2-amine
  • N-bis(2-methylphenoxy)phosphoryl-5-nitro-pyridin-2-amine
  • 3-bromo-5-chloro-n-(2-methoxyethyl)pyridin-2-amine
  • 2-(benzo[d]thiazole-2-carbonyl)-3,4-dihydro-1H-dipyrido[1,2-a:4',3'-d]pyrimidin-11(2H)-one
  • 1-(2-oxo-2-(11-oxo-3,4-dihydro-1H-dipyrido[1,2-a:4',3'-d]pyrimidin-2(11H)-yl)ethyl)pyrrolidine-2,5-dione
  • 2-(3-methoxy-1-methyl-1H-pyrazole-4-carbonyl)-3,4-dihydro-1H-dipyrido[1,2-a:4',3'-d]pyrimidin-11(2H)-one
  • 3-(2-oxo-2-(11-oxo-3,4-dihydro-1H-dipyrido[1,2-a:4',3'-d]pyrimidin-2(11H)-yl)ethyl)benzo[d]oxazol-2(3H)-one
  • 2-(quinoxaline-2-carbonyl)-3,4-dihydro-1H-dipyrido[1,2-a:4',3'-d]pyrimidin-11(2H)-one
  • 2-(3-(phenylsulfonyl)propanoyl)-3,4-dihydro-1H-dipyrido[1,2-a:4',3'-d]pyrimidin-11(2H)-one
  • 2-(1-(thiophen-2-yl)cyclopentanecarbonyl)-3,4-dihydro-1H-dipyrido[1,2-a:4',3'-d]pyrimidin-11(2H)-one
  • 2-(1-methyl-3-(thiophen-2-yl)-1H-pyrazole-5-carbonyl)-3,4-dihydro-1H-dipyrido[1,2-a:4',3'-d]pyrimidin-11(2H)-one
  • 2-(2-(6-oxopyridazin-1(6H)-yl)acetyl)-3,4-dihydro-1H-dipyrido[1,2-a:4',3'-d]pyrimidin-11(2H)-one
  • 3-(11-oxo-2,3,4,11-tetrahydro-1H-dipyrido[1,2-a:4',3'-d]pyrimidine-2-carbonyl)pyridine 1-oxide
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