1H-Pyrazol-5-amine, 3-(4-bromophenyl)-1-(4-(4-bromophenyl)-2-thiazolyl)-

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Names

[ CAS No. ]:
74101-15-8

[ Name ]:
1H-Pyrazol-5-amine, 3-(4-bromophenyl)-1-(4-(4-bromophenyl)-2-thiazolyl)-

[Synonym ]:
5-(4-bromo-phenyl)-2-[4-(4-bromo-phenyl)-thiazol-2-yl]-2H-pyrazol-3-ylamine

Chemical & Physical Properties

[ Density]:
1.79g/cm3

[ Boiling Point ]:
675.6ºC at 760 mmHg

[ Molecular Formula ]:
C18H12Br2N4S

[ Molecular Weight ]:
476.18800

[ Flash Point ]:
362.4ºC

[ Exact Mass ]:
473.91500

[ PSA ]:
84.97000

[ LogP ]:
6.35120

[ Index of Refraction ]:
1.771

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ4893500
CHEMICAL NAME :
1H-Pyrazol-5-amine, 3-(4-bromophenyl)-1-(4-(4-bromophenyl)-2-thiazolyl)-
CAS REGISTRY NUMBER :
74101-15-8
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C18-H12-Br2-N4-S
MOLECULAR WEIGHT :
476.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including Medicinal Chemistry. (Publications & Information Directorate, Council of Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012, India) V.14B- 1976- Volume(issue)/page/year: 18,424,1979

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-(4-Bromphenyl)-3-oxopropanonitril
  • [4-(4-bromophenyl)-1,3-thiazol-2-yl]hydrazine

DownStream

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • N-[1-(6-cyclopropylpyrimidin-4-yl)piperidin-3-yl]-N-methylmethanesulfonamide
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide