4-diphenoxyphosphorylmorpholine

Names

[ CAS No. ]:
7412-25-1

[ Name ]:
4-diphenoxyphosphorylmorpholine

[Synonym ]:
Morpholino-phosphonsaeure-diphenylester
4-Morpholinephosphonic acid,diphenyl ester
Diphenyl 4-morpholinylphosphonate
Diphenyl morpholinophosphonate
morpholin-4-yl-phosphonic acid diphenyl ester
OR&WLN: T6N DOTJ APO&Phosphonic acid,morpholino-,diphenyl ester

Chemical & Physical Properties

[ Density]:
1.28g/cm3

[ Boiling Point ]:
432ºC at 760 mmHg

[ Molecular Formula ]:
C16H18NO4P

[ Molecular Weight ]:
319.29200

[ Flash Point ]:
215ºC

[ Exact Mass ]:
319.09700

[ PSA ]:
57.81000

[ LogP ]:
3.52260

[ Index of Refraction ]:
1.591

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SZ9680000
CHEMICAL NAME :
Phosphonic acid, morpholino-, diphenyl ester
CAS REGISTRY NUMBER :
7412-25-1
BEILSTEIN REFERENCE NO. :
0299323
LAST UPDATED :
199706
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C16-H18-N-O4-P
MOLECULAR WEIGHT :
319.32
WISWESSER LINE NOTATION :
T6N DOTJ APO&OR&OR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 5,287,1953
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 5,138,1953

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • morpholine
  • Diphenyl phosphate
  • Diphenyl chlorophosphate

DownStream

  • Dimethyl morpholinophosphoramidate.

Related Compounds

  • 4-Amino-2-chloro-5-(1H-tetrazol-5-yl)benzenesulfonamide
  • 4-(4-Chlorophenyl)-4-Bromopiperide
  • 4-(2-nitroimidazol-1-yl)butane-1,2-diol
  • 4-Iodo-1H-indazole-3-carboxylic acid
  • 4-chlorooxolan-3-ol,formic acid
  • 4,6-Pyrimidinedicarboxylic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 1-(2-Chloro-6-methylphenyl)piperazine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide