Imiclopazine

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Names

[ CAS No. ]:
7414-95-1

[ Name ]:
Imiclopazine

[Synonym ]:
Chlorimpiphenine dihydrochloride
Chorimpiphenine
P-4241
Chlorimiphene dichloride
Ponsital
Imiclopazine hydrochloride
Chlorimphenine hydrochloride
Imiclopazine dihydrochloride
Asta p 4241

Chemical & Physical Properties

[ Density]:
1.252g/cm3

[ Boiling Point ]:
659.8ºC at 760mmHg

[ Molecular Formula ]:
C25H32ClN5OS

[ Molecular Weight ]:
486.07200

[ Flash Point ]:
352.8ºC

[ Exact Mass ]:
485.20200

[ PSA ]:
58.57000

[ LogP ]:
4.13440

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NJ0621400
CHEMICAL NAME :
2-Imidazolidinone, 1-(2-(4-(3-(2-chlorophenothiazin-10-yl)propyl)-1-pipe razinyl)ethyl)-3- methyl-, dihydrochloride
CAS REGISTRY NUMBER :
7414-95-1
LAST UPDATED :
198910
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C25-H32-Cl-N5-O-S.2Cl-H
MOLECULAR WEIGHT :
559.05
WISWESSER LINE NOTATION :
T C666 BN ISJ EG B3- AT6N DNTJ D2- AT5NVNTJ C1 &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
321 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 17,317,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 17,317,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
68 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 17,317,1967

Related Compounds

  • imiclopazine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-(2-oxo-5-phenyl-1H-pyridin-3-yl)acetonitrile
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 4-chloro-N-[4-oxo-5-[[3-(trifluoromethyl)phenyl]methyl]-1,3-thiazolidin-2-ylidene]benzamide
  • 2-amino-1-(1-methyl-1H-pyrazol-4-yl)ethan-1-one dihydrochloride
  • Methyl 4-bromo-6-fluoronicotinate
  • 1-(2-Fluoro-3-methoxyphenyl)piperazine hydrochloride
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol