Imiclopazine

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Names

[ Name ]:
Imiclopazine

[Synonym ]:
Chlorimpiphenine dihydrochloride
Chorimpiphenine
P-4241
Chlorimiphene dichloride
Ponsital
Imiclopazine hydrochloride
Chlorimphenine hydrochloride
Imiclopazine dihydrochloride
Asta p 4241

Chemical & Physical Properties

[ Density]:
1.252g/cm3

[ Boiling Point ]:
659.8ºC at 760mmHg

[ Molecular Formula ]:
C₂₅H₃₂ClN₅OS

[ Molecular Weight ]:
486.07200

[ Flash Point ]:
352.8ºC

[ Exact Mass ]:
485.20200

[ PSA ]:
58.57000

[ LogP ]:
4.13440

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NJ0621400

CHEMICAL NAME :: 2-Imidazolidinone, 1-(2-(4-(3-(2-chlorophenothiazin-10-yl)propyl)-1-pipe razinyl)ethyl)-3- methyl-, dihydrochloride

CAS REGISTRY NUMBER :: 7414-95-1

LAST UPDATED :: 198910

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C25-H32-Cl-N5-O-S.2Cl-H

MOLECULAR WEIGHT :: 559.05

WISWESSER LINE NOTATION :: T C666 BN ISJ EG B3- AT6N DNTJ D2- AT5NVNTJ C1 &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 321 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 17,317,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 17,317,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 68 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 17,317,1967

Related Compounds

imiclopazine
Octahydro-5-hydroxy-4,7-methano-1H-indene-5-propanol
4-Methyl-2-(1,2,3,4-tetrahydro-1,4-methanonaphthalen-6-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
2-(1,3-Dihydro-1,1,3,3-tetramethyl-5-isobenzofuranyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
2-(1,2,3,4-Tetrahydro-1,4-epoxynaphthalen-6-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
2-(2,3-Dihydro-1,1,2,2,3,3-hexamethyl-1h-inden-5-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
(E)-N-Cyclopropyl-4-(dimethylamino)-N-[[4-(1,2,4-triazol-1-yl)phenyl]methyl]but-2-enamide
(E)-4-(Dimethylamino)-N-[1-(1-methylsulfonylcyclopropyl)ethyl]but-2-enamide
(2E)-4-(dimethylamino)-N-(2-methoxy-4-phenylcyclohexyl)but-2-enamide
(E)-4-(Dimethylamino)-N-[1-(1-ethylsulfonylpiperidin-4-yl)ethyl]-N-methylbut-2-enamide
N-[(4-Prop-2-ynoxyphenyl)methyl]but-2-ynamide

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