Molindone
Suppliers
Names
[ CAS No. ]:
7416-34-4
[ Name ]:
Molindone
[Synonym ]:
3-ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one
MOLINDONE
molidone hydrochloride
EN-1733A
Chemical & Physical Properties
[ Density]:
1.14 g/cm3
[ Boiling Point ]:
462.9ºC at 760 mmHg
[ Melting Point ]:
180 - 181ºC
[ Molecular Formula ]:
C16H24N2O2
[ Molecular Weight ]:
276.37400
[ Flash Point ]:
233.7ºC
[ Exact Mass ]:
276.18400
[ PSA ]:
45.33000
[ LogP ]:
1.90070
[ Index of Refraction ]:
1.559
[ Water Solubility ]:
H2O: 19 mg/mL
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NM3300000
- CHEMICAL NAME :
- Indol-4(5H)-one, 3-ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)-
- CAS REGISTRY NUMBER :
- 7416-34-4
- LAST UPDATED :
- 199801
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C16-H24-N2-O2
- MOLECULAR WEIGHT :
- 276.42
- WISWESSER LINE NOTATION :
- T56 BM FV&TJ C1 D2 G1- AT6N DOTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 714 ug/kg/D
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - antipsychotic
- REFERENCE :
- 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,402,1969
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 4285 ug/kg/3D-I
- TOXIC EFFECTS :
- Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- REFERENCE :
- JCLPDE Journal of Clinical Psychiatry. (Physicians Postgraduate Press, Inc., POB 240008, Memphis, TN 38124) V.39- 1978- Volume(issue)/page/year: 47,607,1986
Safety Information
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
22
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
NM3325000