Losmiprofen

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Names

[ CAS No. ]:
74168-08-4

[ Name ]:
Losmiprofen

[Synonym ]:
Losmiprofen

Chemical & Physical Properties

[ Density]:
1.286g/cm3

[ Boiling Point ]:
469.4ºC at 760 mmHg

[ Molecular Formula ]:
C17H15ClO4

[ Molecular Weight ]:
318.75200

[ Flash Point ]:
237.7ºC

[ Exact Mass ]:
318.06600

[ PSA ]:
63.60000

[ LogP ]:
3.73130

[ Index of Refraction ]:
1.586

[ Storage condition ]:
2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UE8758000
CHEMICAL NAME :
Propionic acid, 2-(3-(p-chlorobenzoyl)-o-tolyloxy)-
CAS REGISTRY NUMBER :
74168-08-4
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C17-H15-Cl-O4
MOLECULAR WEIGHT :
318.77
WISWESSER LINE NOTATION :
QVY1&OR B1 CVR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 15,457,1980

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl 2-[3-(4-chlorobenzoyl)-2-methylphenoxy]propanoate

DownStream

Related Compounds

  • N-(4-fluoro-3-methylphenyl)-4-hydrazinyl-6-methylpyrimidin-2-amine
  • N-(4-fluorophenyl)-4-hydrazinyl-6-methylpyrimidin-2-amine
  • {6-Chloro-4-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]quinolin-3-yl}(morpholin-4-yl)methanone
  • 1-(4-{4-[6-Chloro-3-(morpholin-4-ylcarbonyl)quinolin-4-yl]piperazin-1-yl}phenyl)ethanone
  • {6-Chloro-4-[4-(pyridin-2-yl)piperazin-1-yl]quinolin-3-yl}(morpholin-4-yl)methanone
  • 6-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]-3-(morpholine-4-carbonyl)quinoline
  • 4-hydrazinyl-6-methyl-N-(2-methylphenyl)pyrimidin-2-amine
  • N-(3,5-dimethylphenyl)-4-hydrazinyl-6-methylpyrimidin-2-amine
  • N-(3-fluoro-4-methylphenyl)-4-hydrazinyl-6-methylpyrimidin-2-amine
  • 1-(4-Chlorophenyl)-1,4-dihydropyrazine-2,3-dione
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