Losmiprofen

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Names

[ CAS No. ]:
74168-08-4

[ Name ]:
Losmiprofen

[Synonym ]:
Losmiprofen

Chemical & Physical Properties

[ Density]:
1.286g/cm3

[ Boiling Point ]:
469.4ºC at 760 mmHg

[ Molecular Formula ]:
C17H15ClO4

[ Molecular Weight ]:
318.75200

[ Flash Point ]:
237.7ºC

[ Exact Mass ]:
318.06600

[ PSA ]:
63.60000

[ LogP ]:
3.73130

[ Index of Refraction ]:
1.586

[ Storage condition ]:
2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UE8758000
CHEMICAL NAME :
Propionic acid, 2-(3-(p-chlorobenzoyl)-o-tolyloxy)-
CAS REGISTRY NUMBER :
74168-08-4
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C17-H15-Cl-O4
MOLECULAR WEIGHT :
318.77
WISWESSER LINE NOTATION :
QVY1&OR B1 CVR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 15,457,1980

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl 2-[3-(4-chlorobenzoyl)-2-methylphenoxy]propanoate

DownStream

Related Compounds

  • Ethyl 4-(3,3-dimethylpiperazin-1-yl)benzoate
  • methyl 3-methoxy-1-methyl-1H-pyrazole-4-carboxylate
  • 4-(Isoindolin-2-Ylsulfonyl)benzene-1,3-Diol
  • 2-bromo-6-{[tert-butyl(dimethyl)silyl]oxy}-N,N-diethylbenzamide
  • 3-Chloro-4,6-dimethoxy-2-methylbenzoic acid
  • Methyl 5-chloro-2,4-bis(methoxymethoxy)benzoate
  • N-prop-2-enyl-2,3-dihydro-1H-isoindole-1-carboxamide
  • Methyl 4-{1-[5-chloro-2,4-bis(methoxymethoxy)benzoyl]pyrrolidin-2-yl}-3-methylbenzoate
  • Methyl 2-methyl-3-pyrrolidin-2-ylbenzoate
  • 4-Bromo-3-methylthieno[2,3-b]pyridine
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