DL-4-Chlorophenylalanine

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Names

[ CAS No. ]:
7424-00-2

[ Name ]:
DL-4-Chlorophenylalanine

[Synonym ]:
L-4-Chlorophenylalanine
para-Chlorophenylalanine
2-amino-3-(4-chlorophenyl)propanoic acid
PCP,PCPA
p-Cl-L-Phe-OH
p-Chloro-L-phenylalanine
H-DL-PHE(4-CL)-OH
EINECS 231-051-9
4-Chlorophenylalanine
fenchlonine
RS-4-chlorophenylalanine
DL-Phe(4-Cl)-OH
4-Chloro-phenylalanine
Phenylalanine, 4-chloro-
DL-p-Chlorophenylalanine
4-Chloro-DL-phenylalanine
MFCD00002601
p-Chlorophenylalanine
fenclonin
3-(p-chlorophenyl) alanine
Fenclonine
cp10,188
(2S)-2-amino-3-(4-chlorophenyl)propanoic acid
c-pal
4-Cl-DL-Phe
PCP
(S)-4-Chlorophenylalanine
L-p-Chlorophenylalanine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
339.5±32.0 °C at 760 mmHg

[ Melting Point ]:
>240 °C (dec.)(lit.)

[ Molecular Formula ]:
C9H10ClNO2

[ Molecular Weight ]:
199.634

[ Flash Point ]:
159.1±25.1 °C

[ Exact Mass ]:
199.040009

[ PSA ]:
63.32000

[ LogP ]:
1.71

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.590

[ Storage condition ]:
−20°C

[ Water Solubility ]:
slightly soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AY4390010
CHEMICAL NAME :
Alanine, 3-(p-chlorophenyl)-, DL-
CAS REGISTRY NUMBER :
7424-00-2
BEILSTEIN REFERENCE NO. :
2805758
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H10-Cl-N-O2
MOLECULAR WEIGHT :
199.65
WISWESSER LINE NOTATION :
QVYZ1R DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
1794 mg/kg
SEX/DURATION :
female 14-19 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
BIMDA2 Biochemical Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967- Volume(issue)/page/year: 4,516,1970

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H317

[ Precautionary Statements ]:
P280-P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R25;R43

[ Safety Phrases ]:
S36/37-S45

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
AY4390010

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Propanedioic acid,2-(acetylamino)-2-[(4-chlorophenyl)methyl]-, 1,3-diethyl ester
  • 4-Chlorobenzyl chloride
  • 1,1-dichloro-3-(4-chloro-phenyl)-propene
  • (4-chlorobenzylideneamino)acetic acid ethyl ester
  • 4-Chlorobenzyl bromide
  • 5(4H)-Oxazolone,4-[(4-chlorophenyl)methylene]-2-phenyl-
  • Ethyl 4-chlorophenylalaninate hydrochloride (1:1)
  • 4-Chlorobenzaldehyde

DownStream

  • Ethyl 4-chlorophenylalaninate hydrochloride (1:1)
  • Phenylacetic acid
  • D-4-Chlorophenylalanine
  • 2-Amino-3-(4-chlorophenyl)-1-propanol
  • 3-(4-CHLORO-PHENYL)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-PROPIONIC ACID
  • BENZENEPROPANOIC ACID, 4-CHLORO-.ALPHA.-OXO-
  • Fenclonine
  • 1-Chlorooctane

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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Related Compounds

  • Dl-4-Chlorophenylalanine
  • N-benzyloxycarbonyl-DL-4-chlorophenylalanine
  • dl-4-chlorophenylalanine ethyl ester hydrochloride
  • DL-4-Chlorophenylalanine methyl ester hydrochloride
  • DL-4-Chlorophenylalanine methyl ester hydrochloride
  • DL-4-Chlorophenylalanine methyl ester hydrochloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 2-[3-(2,2,2-trifluoroacetamido)-1H-pyrazol-1-yl]pentanoic acid
  • tert-butyl 3-{[(1R,2R)-2-fluorocyclopentyl]amino}propanoate
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 1,1-Difluoro-3-(3-fluoro-4-methoxyphenyl)-2-methylpropan-2-amine
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde