3-Methyl-11H-1,2,4-triazolo(4,3:2,3)pyridazino(4,5-b)indole

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Names

[ CAS No. ]:
74378-08-8

[ Name ]:
3-Methyl-11H-1,2,4-triazolo(4,3:2,3)pyridazino(4,5-b)indole

[Synonym ]:
11-guanidinoundecanamide
Undecanamide,11-[(aminoiminomethyl)amino]-,sulfate (2:1)

Chemical & Physical Properties

[ Density]:
1.58g/cm3

[ Boiling Point ]:
634.5ºC at 760 mmHg

[ Molecular Formula ]:
C12H9N5

[ Molecular Weight ]:
223.23300

[ Flash Point ]:
337.5ºC

[ Exact Mass ]:
223.08600

[ PSA ]:
58.87000

[ LogP ]:
2.06720

[ Index of Refraction ]:
1.866

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XZ5495850
CAS REGISTRY NUMBER :
74378-08-8
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H9-N5
MOLECULAR WEIGHT :
223.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
794 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 71,1406,1982

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • acetic acid
  • 3,5-Dihydro-4H-pyridazino(4,5-b)indol-4-one hydrazone

DownStream

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 1-(5-(5-bromo-2-hydroxyphenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • (2Z)-6-[2-(3,4-dimethoxyphenyl)-2-oxoethoxy]-2-[(2-methyl-2H-chromen-3-yl)methylidene]-1-benzofuran-3(2H)-one
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 4-(5-phenyl-1,3,4-oxadiazol-2-yl)-1H-pyrazol-3-amine