2(3H)-Benzothiazolethione,6-amino-

Names

[ CAS No. ]:
7442-07-1

[ Name ]:
2(3H)-Benzothiazolethione,6-amino-

[Synonym ]:
6-amino-3H-1,3-benzothiazole-2-thione
EINECS 231-184-2
MFCD00059164

Chemical & Physical Properties

[ Density]:
1.54g/cm3

[ Boiling Point ]:
267-272°C

[ Melting Point ]:
267-272 °C(lit.)

[ Molecular Formula ]:
C₇H₆N₂S₂

[ Molecular Weight ]:
182.26600

[ Flash Point ]:
195.7ºC

[ Exact Mass ]:
181.99700

[ PSA ]:
105.95000

[ LogP ]:
2.74840

[ Index of Refraction ]:
1.83

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DL6488000

CHEMICAL NAME :: 2-Benzothiazolethiol, 6-amino-

CAS REGISTRY NUMBER :: 7442-07-1

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C7-H6-N2-S2

MOLECULAR WEIGHT :: 182.27

WISWESSER LINE NOTATION :: T56 BN DSJ CSH GZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,12,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DL6488000

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

6-nitro-1,3-benzothiazole-2-thiol
Carbon disulphide
Benzenethiol, 2,5-diamino- (9CI)
2-Aminothiophenol
2-Mercaptobenzothiazole
2-chloro-6-nitrobenzo[d]thiazole
Ethanol

DownStream

N-(2-methylsulfanyl-1,3-benzothiazol-6-yl)benzamide
2-(methylthio)-1,3-benzothiazol-6-amine
Urea, (2,3-dihydro-2-thioxo-6-benzothiazolyl)- (9CI)
2(3H)-Benzothiazolethione,6-(ethylamino)-(9CI)
BIR2
2-benzylsulfanyl-1,3-benzothiazol-6-amine
2-(PROPYLTHIO)BENZO[D]THIAZOL-6-AMINE

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

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ChemMedChem 6(4) , 654-66, (2011)

Small molecules, namely coactivator binding inhibitors (CBIs), that block estrogen signaling by directly inhibiting the interaction of the estrogen receptor (ER) with coactivator proteins act in a fun...

[A QSAR study of synthetic stimulators of growth of domestic animals on the basis of 6-amino-2-mercaptobenzothiazole].

Cesk. Farm. 37(10) , 440-2, (1988)

Electrochemical Characterization of Gold 6-Amino-2-mercaptobenzothiazole Self-Assembled Monolayer for Dopamine Detection in Pharmaceutical Samples. Shervedani RK, et al.

Electroanalysis 22(9) , 969-977, (2010)

2(3H)-Benzothiazolethione,6-amino-5-chloro-(9CI)
2(3H)-Benzothiazolethione,6-nitro-3-[[[2-(2-propen-1-ylthio)-6-benzothiazolyl]amino]methyl]-
2(3H)-Benzothiazolethione, 6,7-dihydro-6,7-dihydroxy-, (6R,7R)-rel- (9CI)
2(3H)-Benzothiazolethione,6-(methylamino)-(9CI)
2(3H)-Benzothiazolethione,6-(2-propenylamino)-(9CI)
2(3H)-Benzothiazolethione,6-(2-propynylamino)-(9CI)
Methyl (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoate
3-cyclopropyl-1-[(1-methyl-1H-1,3-benzodiazol-2-yl)(phenyl)methyl]urea
[(2R,3R,4R,5R)-2-[5-Fluoro-2-oxo-4-(pentoxycarbonylamino)pyrimidin-1-yl]-4-hydroxy-5-methyloxolan-3-yl] acetate
5-(Methoxycarbonyl)-4-phenylthiophene-2-carboxylic acid
3-Amino-2-methyl-3-thioxopropanoic acid
2-methyl-N-phenylpyrimidin-4-amine
1-(5-Chlorofuran-2-yl)ethan-1-amine
3-Fluoromethyl-5-methyl-benzonitrile
2-Methyl-6-(pyrrolidin-1-yl)hexan-3-one
Benzoic acid, 4-[5-[bis(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl]-2-furanyl]-, propyl ester

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