Imipenem

Suppliers

Names

[ Name ]:
Imipenem

[Synonym ]:
1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, (5R,6S)-, hydrate (1:1)
(5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid monohydrate
(5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-en-2-carbonsäurehydrat
(5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate (1:1)
Imipenem hydrate
N-Formimidoylthienamycin Monohydrate
MFCD08458212
Imipenem monohydrate
Imipenem, Monohydrate
EINECS 264-734-5
1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, (5R,6S)-, monohydrate
acide (5R,6S)-6-[(1R)-1-hydroxyéthyl]-3-({2-[(iminométhyl)amino]éthyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ène-2-carboxylique hydrate
[5R-[5a,6a(R*)]]-6-(1-Hydroxyethyl)-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Monohydrate
(5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate
Imipenem

Chemical & Physical Properties

[ Density]:
1.02 g/mL at 25 °C

[ Boiling Point ]:
34.6°C

[ Melting Point ]:
-116.3°C

[ Molecular Formula ]:
C₁₂H₁₉N₃O₅S

[ Molecular Weight ]:
317.36

[ Flash Point ]:
<−30 °F

[ Exact Mass ]:
317.104553

[ PSA ]:
148.25000

[ LogP ]:
0.18820

[ Storage condition ]:
-20°C Freezer

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
F+,C,F

[ Risk Phrases ]:
R12:Extremely Flammable. R14/15:Reacts violently with water, liberating extremely flammable gases . R19:May form explosive peroxides. R22:Harmful if swallowed. R34:Causes burns. R66:Repeated exposure may cause skin dryness or cracking. R67:Vapors may cause

[ Safety Phrases ]:
S16-S26-S36/37/39-S43-S45-S7/8-S27

[ RIDADR ]:
UN 3399 4.3/PG 1

[ WGK Germany ]:
1

[ Packaging Group ]:
I

[ Hazard Class ]:
4.3

Articles

Combined disc methods for the detection of KPC- and/or VIM-positive Klebsiella pneumoniae: improving reliability for the double carbapenemase producers.

Clin. Microbiol. Infect. 19(9) , E412-5, (2013)

Klebsiella pneumoniae strains co-producing klebsiella pneumoniae carbapenemase (KPC) and verona integron-encoded metallo-beta-lactamase (VIM) are frequently isolated in Greece and have also occurred i...

Inhibitory Potential of Twenty Five Anti-tuberculosis Drugs on CYP Activities in Human Liver Microsomes.

Biol. Pharm. Bull. 38 , 1425-9, (2015)

The direct inhibitory potential of twenty five anti-tuberculosis drugs on eight CYP-specific reactions in human liver microsomes was investigated to predict in vivo drug-drug interactions (DDIs) from ...

Colistin and doripenem combinations against Pseudomonas aeruginosa: profiling the time course of synergistic killing and prevention of resistance.

J. Antimicrob. Chemother. 70 , 1434-42, (2015)

Colistin is an 'old' drug, which is being increasingly utilized due to limited therapeutic options. However, resistance emergence during monotherapy is concerning. Here, our objective was to optimize ...